Recombinant Rat Cathepsin C/DPPI Protein, CF | R&D Systems 8285-CY-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat Cathepsin C/DPPI Protein, CF

catalog :

8285-CY-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Sutton V, Watt S, Akhlaghi H, Cipolla D, Chen K, LaSala D, et al. Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells. Front Pharmacol. 2024;15:1396710 pubmed publisher

product information

master code :

8285-CY

SKU :

8285-CY-010

product name :

Recombinant Rat Cathepsin C/DPPI Protein, CF

unit size :

10 ug

description :

The Recombinant Rat Cathepsin C/DPPI Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat Cathepsin C/DPPI Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Cathepsin C/DPPI

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in MES and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane

species :

Rat

observed molecular weight :

56-62 kDa, reducing conditions

theoretical molecular weight :

51 kDa

gene symbol :

Ctsc

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Arg-7-amido-4-methylcoumarin (GR-AMC). The specific activity is 25,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<0.1 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P80067

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived rat Cathepsin C/DPPI protein Asp25-Leu462, with a C-terminal 10-His tag

source short :

NS0

USD :

432 USD

alt names :

cathepsin CEC 3.4.14.1, Cathepsin J, CPPIHMS, CTSC, dipeptidyl peptidase 1, Dipeptidyl peptidase I, Dipeptidyl transferase, dipeptidyl-peptidase I, DPP1, DPPI, DPP-I, JP, JPD, PALS, PLS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage