product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Activin B Protein, CF
catalog :
8260-AB-010/CF
quantity :
10 ug
price :
373 USD
more info or order :
R&D Systems product webpage
citations: 5
Reference
Yamamoto T, Diao Z, Murakami M, Shimokawa F, Matsui T, Funaba M. Factors affecting the induction of uncoupling protein 1 in C2C12 myogenic cells. Cytokine. 2022;157:155936 pubmed publisher
Wang X, Tang P, Guo F, Zhang M, Yan Y, Huang M, et al. mDia1 and Cdc42 Regulate Activin B-Induced Migration of Bone Marrow-Derived Mesenchymal Stromal Cells. Stem Cells. 2019;37:150-162 pubmed publisher
Goh B, Singhal V, Herrera A, Tomlinson R, Kim S, Faugere M, et al. Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass. J Biol Chem. 2017;292:13809-13822 pubmed publisher
Zhang L, Xu P, Wang X, Zhang M, Yan Y, Chen Y, et al. Activin B regulates adipose-derived mesenchymal stem cells to promote skin wound healing via activation of the MAPK signaling pathway. Int J Biochem Cell Biol. 2017;87:69-76 pubmed publisher
Guo T, Marmol P, Moliner A, Björnholm M, Zhang C, Shokat K, et al. Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity. elife. 2014;3:e03245 pubmed publisher
product information
master code :
8260-AB/CF
SKU :
8260-AB-010/CF
product name :
Recombinant Mouse Activin B Protein, CF
unit size :
10 ug
description :
The Recombinant Mouse Activin B Protein, CF from R&D Systems is derived from HEK293. The Recombinant Mouse Activin B Protein, CF has been validated for the following applications: Binding Activity.
target :
Activin B
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in HCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE with silver staining.
species :
Mouse
observed molecular weight :
12 kDa, reducing conditions
theoretical molecular weight :
13 kDa (monomer)
gene symbol :
Inhbb
details of functionality :
Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. etáal . (1991) Method Enzymol. 198 :340. The ED50 for this effect is 0.2-1.2 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Mouse Activin B Protein Bioactivity
accessionNumbers :
Q04999
applications :
Binding Activity
source long :
Human embryonic kidney cell, HEK293-derived mouse Activin B protein Gly297-Ala411
source short :
HEK293
USD :
373 USD
alt names :
activin AB beta polypeptide, Activin beta-B chain, INHBB, inhibin beta B chain, inhibin, beta B, inhibin, beta B (activin AB beta polypeptide), Inhibin, beta-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.