Recombinant Human Galectin-3 (Human Cell-expressed), CF | R&D Systems 8259-GA product information

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product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Galectin-3 (Human Cell-expressed), CF

catalog :

8259-GA

quantity :

50 ug

price :

329 USD

citations: 2

Reference
Tao C, Cheng K, Ma Y, Hsu W, Chen Y, Fuh J, et al. Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease. Cell Death Differ. 2019;: pubmed publisher
Mathew M, Donaldson J. Distinct cargo-specific response landscapes underpin the complex and nuanced role of galectin-glycan interactions in clathrin-independent endocytosis. J Biol Chem. 2018;293:7222-7237 pubmed publisher

product information

brand :

R&D Systems

master code :

8259-GA

SKU :

8259-GA-050

product name :

Recombinant Human Galectin-3 (Human Cell-expressed), CF

description :

The Recombinant Human Galectin-3 (Human Cell-expressed), CF from R&D Systems is derived from HEK293. The Recombinant Human Galectin-3 (Human Cell-expressed), CF has been validated for the following applications: Bioactivity.

target :

Galectin-3

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in HEPES, NaCl, TCEP, PEG and Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

26-31 kDa, reducing conditions

theoretical molecular weight :

25 kDa

gene symbol :

LGALS3

details of functionality :

Measured by its ability to support the adhesion of MOLT-4 human acute lymphoblastic leukemia cells. The ED50 for this effect id 0.6-3 µg/mL. Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al . (2000) J. Cell Sci. 113 :2385. The ED50 for this effect is 3-10 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

8259-GA

accessionNumbers :

P17931

applications :

Bioactivity

source :

Human embryonic kidney cell, HEK293-derived human Galectin-3 protein Ala2-Ile250

2020 USD :

329

2021 USD :

329 USD

alt names :

AGE-R3, Carbohydrate-binding protein 35, CBP 35,35 kDa lectin, CBP35, Gal-3, GAL3, galactin-3, Galactose-specific lectin 3, Galactoside-binding protein, GALBPCBP35, galectin-3, Galectin3, GALIG, IgE-binding protein, L29, L31, L-31, Laminin-binding protein, Lectin L-29, lectin, galactoside-binding, soluble, 3, LGALS2, LGALS3, Mac-2, Mac-2 antigen, MAC2GAL3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.