Recombinant Human Angiopoietin-like 4 N-Terminal Frag, CF | R&D Systems 8249-AN-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Angiopoietin-like 4 N-Terminal Frag, CF

catalog :

8249-AN-050

quantity :

50 ug

price :

475 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Hefni E, Menon D, Ma T, Asiedu E, Sultan A, Meiller T, et al. Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway. Cell Signal. 2023;108:110697 pubmed publisher
Baba K, Kitajima Y, Miyake S, Nakamura J, Wakiyama K, Sato H, et al. Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines. Sci Rep. 2017;7:11127 pubmed publisher

product information

master code :

8249-AN

SKU :

8249-AN-050

product name :

Recombinant Human Angiopoietin-like 4 N-Terminal Frag, CF

unit size :

50 ug

description :

The Recombinant Human Angiopoietin-like 4 N-Terminal Frag, CF from R&D Systems is derived from CHO. The Recombinant Human Angiopoietin-like 4 N-Terminal Frag, CF has been validated for the following applications: Bioactivity.

target :

Angiopoietin-like Protein 4/ANGPTL4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MOPS, NaCl and CHAPS.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

18-22 kDa (major) and 32-70 kDa, reducing conditions

theoretical molecular weight :

17 kDa

gene symbol :

ANGPTL4

details of functionality :

Measured by its ability to promote the expansion of E16 rat liver mononuclear cells in vitro, in the presence of Recombinant Mouse SCF/c-kit Ligand (Catalog # 455-MC ), Recombinant Mouse Thrombopoietin/Tpo (Catalog # 488-TO ), and Recombinant Mouse Flt-3 Ligand (Catalog # 427-FL ). The ED50 for this effect is 25-125 ng/mL in the presence of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9BY76

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived human Angiopoietin-like Protein 4/ANGPTL4 protein Human ANGPTL4 (Gly26-Arg161) Accession # Q9BY76 GGGSGGGSGGGS 6-His tag N-terminus C-terminus

source short :

CHO

USD :

475 USD

alt names :

Angiopoietin like Protein 4, angiopoietin-like 4, Angiopoietin-like protein 4, ANGPTL4, ARP4fasting-induced adipose factor, FIAF, FIAFhepatic angiopoietin-related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, HFARPANGPTL2, NL2, peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein, PGAR, PGARangiopoietin-related protein 4, pp1158, PPARG angiopoietin related protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage