product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Bcl-w (minus C-Terminus) Protein, CF
catalog :
824-BW-050
quantity :
50 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Cosker K, Pazyra Murphy M, Fenstermacher S, Segal R. Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration. J Neurosci. 2013;33:5195-207 pubmed publisher
product information
master code :
824-BW
SKU :
824-BW-050
product name :
Recombinant Human Bcl-w (minus C-Terminus) Protein, CF
unit size :
50 ug
description :
The Recombinant Human Bcl-w (minus C-Terminus) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Bcl-w (minus C-Terminus) Protein, CF has been validated for the following applications: Inhibition Activity.
target :
Bcl-w
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl and Glycerol.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
18 kDa, under reducing and non-reducing conditions
theoretical molecular weight :
19.5 kDa
gene symbol :
BCL2L2
details of functionality :
Measured by its ability to inhibit Caspase-8-cleaved BID-mediated release of cytochromeác from isolated mouse liver mitochondria using the Rat/Mouse Cytochrome c Quantikine ELISA (Catalog # MCTC0 ) to quantify cytochromeác. The typical EC50 is between 50 and 250 nM in the presence of 54 nM Recombinant Human BID Caspase-8-cleaved (Catalog # 882-B8 ). Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q92843
applications :
Inhibition Activity
source long :
E. coli -derived human Bcl-w protein Ala2-Thr172, with a C-terminal 6-His tag
source short :
E. coli
USD :
468 USD
alt names :
Apoptosis regulator Bcl-W, Bcl2-L-2, BCL2L2, BCL2-like 2, Bclw, BCL-W, BCLWbcl-2-like protein 2, KIAA0271BCL2-L-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.