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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat CD40/TNFRSF5 Fc Chimera Protein, CF
catalog :
8229-CD-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Kobayashi C, Suzuki Imaizumi M, Sakaguchi Y, Ishii T, Adachi M, Kaneda A, et al. The novel and potent CD40 agonist KHK2840 augments the antitumor efficacy of anti-PD-1 antibody and paclitaxel. Cancer Sci. 2024;115:4008-4020 pubmed publisher
product information
master code :
8229-CD
SKU :
8229-CD-050
product name :
Recombinant Rat CD40/TNFRSF5 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Rat CD40/TNFRSF5 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat CD40/TNFRSF5 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CD40/TNFRSF5
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE with silver staining.
species :
Rat
observed molecular weight :
57-63 kDa, reducing conditions
theoretical molecular weight :
46 kDa (monomer)
gene symbol :
Cd40
details of functionality :
Measured by its ability to inhibit CD40 Ligand-induced proliferation of mouse B cells. The ED50 for this effect is 0.1-0.6 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Rat CD40/TNFRSF5 Fc Chimera Protein Bioactivity
accessionNumbers :
Q4QQW2
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived rat CD40/TNFRSF5 protein Rat CD40 (Val24-Arg193) Accession # Q4QQW2 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
B cell surface antigen CD40, B-cell surface antigen CD40, Bp50B cell-associated molecule, CD40, CD40 antigen, CD40 molecule, TNF receptor superfamily member 5, CD40 type II isoform, CD40L receptor, CDw40, MGC9013, nerve growth factor receptor-related B-lymphocyte activation molecule, p50, TNFRSF5, TNFRSF5CD40 antigen (TNF receptor superfamily member 5), tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.