Recombinant Human S100A8/S100A9 Heterodimer Protein, CF | R&D Systems 8226-S8 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human S100A8/S100A9 Heterodimer Protein, CF

catalog :

8226-S8

quantity :

50 ug

price :

369 USD

citations: 4

Reference
Rolfes V, Ribeiro L, Hawwari I, Böttcher L, Rosero N, Maasewerd S, et al. Platelets Fuel the Inflammasome Activation of Innate Immune Cells. Cell Rep. 2020;31:107615 pubmed publisher
Dubois C, Marcé D, Faivre V, Lukaszewicz A, Junot C, Fenaille F, et al. High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients. Sci Rep. 2019;9:15660 pubmed publisher
Sun J, Pan X, Christiansen L, Yuan X, Skovgaard K, Chatterton D, et al. Necrotizing enterocolitis is associated with acute brain responses in preterm pigs. J Neuroinflammation. 2018;15:180 pubmed publisher
Basu A, Munir S, Mulaw M, Singh K, Crisan D, Sindrilaru A, et al. A Novel S100A8/A9 Induced Fingerprint of Mesenchymal Stem Cells associated with Enhanced Wound Healing. Sci Rep. 2018;8:6205 pubmed publisher

product information

brand :

R&D Systems

master code :

8226-S8

SKU :

8226-S8-050

product name :

Recombinant Human S100A8/S100A9 Heterodimer Protein, CF

description :

The Recombinant Human S100A8/S100A9 Heterodimer Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human S100A8/S100A9 Heterodimer Protein, CF has been validated for the following applications: Binding Activity.

target :

S100A8/S100A9 Heterodimer

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS and DTT.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

9 kDa (S100A8) 13 kDa (S100A9), reducing conditions

theoretical molecular weight :

11 kDa (S100A8) 13 kDa (S100A9)

gene symbol :

S100A8

details of functionality :

Measured by its ability to induce IL-6 secretion by A375 human melanoma cells. Hibino, T. et al . (2013) Cancer Res. 73 :172. The ED50 for this effect is 1.5-6 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

8226-S8

accessionNumbers :

P05109 (S100A8) P06702 (S100A9)

applications :

Binding Activity

source :

E. coli -derived human S100A8/S100A9 Heterodimer protein Met1-Glu93 (S100A8) & Thr2-Pro114 (S100A9)

2020 USD :

369

2021 USD :

369 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.