Recombinant Human XIAP (Full Length) Protein, CF | R&D Systems 822-XF-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human XIAP (Full Length) Protein, CF

catalog :

822-XF-050

quantity :

50 ug

price :

458 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Liu R, Wang X, Curtiss C, Sheikh M, Huang Y. Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein. Cell Death Differ. 2020;27:2888-2903 pubmed publisher
Hornburger M, Mayer B, Leonhardt S, Willer E, Zahler S, Beyerle A, et al. A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation. FASEB J. 2014;28:1938-46 pubmed publisher
Park B, Ham Y, Jeong H, Cho S, Je Y, Yoo K, et al. Phosphorylation of Smac by JNK3 attenuates its interaction with XIAP. Biochem Biophys Res Commun. 2007;361:994-9 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

822-XF

SKU :

822-XF-050

product name :

Recombinant Human XIAP (Full Length) Protein, CF

Description :

The Recombinant Human XIAP (Full Length) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human XIAP (Full Length) Protein, CF has been validated for the following applications: Inhibition Activity.

target :

XIAP

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Supplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and Glycerol.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

50-60 kDa, reducing conditions

theoretical molecular weight :

58 kDa

gene symbol :

XIAP

details of functionality :

Measured by its ability to inhibit DEVD-AFC cleavage activity by Recombinant Human Caspase-7 (Catalog # 823-C7 ). The IC50 for inhibition of rhCaspase-7 activity is 50 nM, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAC50373

applications :

Inhibition Activity

source :

E. coli-derived Recombinant Human XIAP (Full Length) Protein

USD :

458 USD

alt names :

API3X-linked inhibitor of apoptosis protein, apoptosis inhibitor 3, baculoviral IAP repeat-containing 4, baculoviral IAP repeat-containing protein 4, BIRC4, BIRC4XLP2, E3 ubiquitin-protein ligase XIAP, EC 6.3.2.-, hIAP3, hIAP-3, hILP, IAP3, IAP-3, IAP-like protein, ILP, ILP1, Inhibitor of apoptosis protein 3, MIHA, X-linked IAP, X-linked inhibitor of apoptosis

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage