Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF | R&D Systems 816-LR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF

catalog :

816-LR

quantity :

100 ug

price :

339 USD

citations: 2

Reference
Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, et al. Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Res Ther. 2011;13:R52 pubmed publisher
Nazarian S, Rahman M, Werden S, Villeneuve D, Meng X, Brunetti C, et al. Yaba monkey tumor virus encodes a functional inhibitor of interleukin-18. J Virol. 2008;82:522-8 pubmed publisher

product information

brand :

R&D Systems

master code :

816-LR

SKU :

816-LR-100

product name :

Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF

description :

The Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF has been validated for the following applications: Bioactivity.

target :

IL-18R alpha/IL-1 R5

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

95-105 kDa, reducing conditions

theoretical molecular weight :

63 kDa (monomer)

gene symbol :

IL18R1

details of functionality :

Measured by its ability to inhibit the IL-18-induced response of KG-1 human acute myelogenous leukemia cells in the presence of soluble Recombinant Human IL-18 R beta/IL-1 R7 Fc Chimera (Catalog # 118-AP ). Approximately 5-15 µg/mL of rhIL-18 Ra/Fc will inhibit 50% of the biological response due to 40 ng/mL of rhIL-18 in the presence of 30 µg/mL of rhIL-18 R beta (AcPL)/Fc Chimera.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

816-LR

accessionNumbers :

Q13478

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human IL-18 R alpha/IL-1 R5 protein Human IL-18 R alpha (Glu20 - Arg329) Accession # Q13478 IEGRDID Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus

2020 USD :

339

2021 USD :

339 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.