product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF
catalog :
816-LR-100
quantity :
100 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Slieker R, Donnelly L, Akalestou E, López Noriega L, Melhem R, G xfc ne x15f A, et al. Identification of biomarkers for glycaemic deterioration in type 2 diabetes. Nat Commun. 2023;14:2533 pubmed publisher
Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, et al. Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Res Ther. 2011;13:R52 pubmed publisher
Nazarian S, Rahman M, Werden S, Villeneuve D, Meng X, Brunetti C, et al. Yaba monkey tumor virus encodes a functional inhibitor of interleukin-18. J Virol. 2008;82:522-8 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
816-LR
SKU :
816-LR-100
product name :
Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF
Description :
The Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF has been validated for the following applications: Bioactivity.
target :
IL-18 R alpha/IL-1 R5
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
95-105 kDa, reducing conditions
theoretical molecular weight :
63 kDa (monomer)
gene symbol :
IL18R1
details of functionality :
Measured by its ability to inhibit the IL-18-induced response of KG-1 human acute myelogenous leukemia cells in the presence of soluble Recombinant Human IL-18 R beta/IL-1 R7 Fc Chimera (Catalog # 118-AP ). Approximately 5-15 µg/mL of rhIL-18 Ra/Fc will inhibit 50% of the biological response due to 40 ng/mL of rhIL-18 in the presence of 30 µg/mL of rhIL-18 R beta (AcPL)/Fc Chimera.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q13478
applications :
Bioactivity
source :
NS0-derived Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera
USD :
423 USD
alt names :
CD218a, CD218a;CDw218a;IL18R1;IL18RA;IL-18Ralpha;IL-18R-alpha;IL18Ralpha2;IL1RRP;IL-1Rrp;Interleukin-18 receptor 1, IL-1 R5, IL-1 Rrp, IL-18 R1, IL18R alpha, IL18R1, IL-18Ra
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.