product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD30/TNFRSF8 Fc Chimera Protein, CF
catalog :
813-CD-100
quantity :
100 ug
price :
458 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Wang R, Li L, Zhang S, Li Y, Wang X, Miao Q, et al. A novel enediyne-integrated antibody-drug conjugate shows promising antitumor efficacy against CD30+ lymphomas. Mol Oncol. 2018;12:339-355 pubmed publisher
Borchmann P, Treml J, Hansen H, Gottstein C, Schnell R, Staak O, et al. The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma. Blood. 2003;102:3737-42 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
813-CD
SKU :
813-CD-100
product name :
Recombinant Human CD30/TNFRSF8 Fc Chimera Protein, CF
Description :
The Recombinant Human CD30/TNFRSF8 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD30/TNFRSF8 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
CD30/TNFRSF8
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
100-125 kDa, reducing conditions
theoretical molecular weight :
66 kDa (monomer)
gene symbol :
TNFRSF8
details of functionality :
Measured by its binding ability in a functional ELISA. When rhCD30 Ligand (Catalog # 1028-CL ) is immobilized at 200 ng/well, the concentration of rhCD30/Fc Chimera that produces 50% of the optimal binding response is found to be approximately 1-5 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P28908.1
applications :
Binding Activity
source :
NS0-derived Recombinant Human CD30/TNFRSF8 Fc Chimera Protein
USD :
458 USD
alt names :
CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.