Recombinant Human uPAR Protein, CF | R&D Systems 807-UK-100/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human uPAR Protein, CF

catalog :

807-UK-100/CF

quantity :

100 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Mukherjee K, Gu C, Collins A, Mettlen M, Samelko B, Altintas M, et al. Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury. Nat Commun. 2022;13:2422 pubmed publisher
Agarwal S, Koh K, Tardi N, Chen C, Dande R, WerneckdeCastro J, et al. Deiodinase-3 is a thyrostat to regulate podocyte homeostasis. EBioMedicine. 2021;72:103617 pubmed publisher
An J, Hyeon J, Jung Y, Choi Y, Kim J, Yang S, et al. Urinary myo-inositol is associated with the clinical outcome in focal segmental glomerulosclerosis. Sci Rep. 2019;9:14707 pubmed publisher
Wei C, Li J, Adair B, Zhu K, Cai J, Merchant M, et al. uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. J Clin Invest. 2019;129:1946-1959 pubmed publisher
Huang J, Liu G, Zhang Y, Cui Z, Wang F, Liu X, et al. Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis. BMC Med. 2014;12:81 pubmed publisher
Zhuang T, Chelluboina B, Ponnala S, Velpula K, Rehman A, Chetty C, et al. Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration. BMC Cancer. 2013;13:590 pubmed publisher
Portelli M, Siedlinski M, Stewart C, Postma D, Nieuwenhuis M, Vonk J, et al. Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J. 2014;28:923-34 pubmed publisher
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

807-UK/CF

SKU :

807-UK-100/CF

product name :

Recombinant Human uPAR Protein, CF

Description :

The Recombinant Human uPAR Protein, CF from R&D Systems is derived from NS0. The Recombinant Human uPAR Protein, CF has been validated for the following applications: Binding Activity.

target :

uPAR

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

40-55 kDa, reducing conditions

theoretical molecular weight :

31 kDa

gene symbol :

PLAUR

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant HumanUPAR at 5 µg/mL (100 µL/well) can bind Recombinant Human u-Plasminogen Activator (uPA)/Urokinase (Catalog # 1310-SE ) with a linear range of 0.3-20 ng/mL.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q03405

applications :

Binding Activity

source :

NS0-derived Recombinant Human uPAR Protein

USD :

447 USD

alt names :

CD87, CD87 antigen, Monocyte activation antigen Mo3, plasminogen activator, urokinase receptor, PLAUR, uPAR, U-PAR, UPARurokinase plasminogen activator surface receptor, u-plasminogen activator receptor form 2, URKRMO3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage