Recombinant Human Kynurenine 3-Monooxygenase/KMO Protein, CF | R&D Systems 8050-KM-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Kynurenine 3-Monooxygenase/KMO Protein, CF

catalog :

8050-KM-025

quantity :

25 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Nahomi R, Nam M, Rankenberg J, Rakete S, Houck J, Johnson G, et al. Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice. Int J Mol Sci. 2020;21: pubmed publisher
Jacobs K, Guillemin G, Lovejoy D. Development of a Rapid Fluorescence-Based High-Throughput Screening Assay to Identify Novel Kynurenine 3-Monooxygenase Inhibitor Scaffolds. SLAS Discov. 2018;23:554-560 pubmed publisher

product information

master code :

8050-KM

SKU :

8050-KM-025

product name :

Recombinant Human Kynurenine 3-Monooxygenase/KMO Protein, CF

unit size :

25 ug

description :

The Recombinant Human Kynurenine 3-Monooxygenase/KMO Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Kynurenine 3-Monooxygenase/KMO Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Kynurenine 3-Monooxygenase/KMO

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and Brij-35.

conjugate :

Unconjugated

purity :

>80%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane

species :

Human

observed molecular weight :

40-45 kDa, reducing conditions

theoretical molecular weight :

51 kDa

gene symbol :

KMO

details of functionality :

Measured by the consumption of NADPH by hydroxylation of L-kynurenine to 3-hydroxy-kynurenine. The specific activity is 290 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O15229

applications :

Enzyme Activity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human Kynurenine 3-Monooxygenase/KMO protein Asp2-Leu441, with an N-terminal Met and 6-His tag

source short :

Sf 21 (baculovirus)

USD :

541 USD

alt names :

KMO, Kynurenine 3Monooxygenase, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage