Recombinant Human CCL16/HCC-4 Protein | R&D Systems 802-HC-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL16/HCC-4 Protein

catalog :

802-HC-025

quantity :

25 ug

price :

252 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Picher Martel V, Boutej H, V xe9 zina A, Cordeau P, Kaneb H, Julien J, et al. Distinct Plasma Immune Profile in ALS Implicates sTNFR-II in pAMPK/Leptin Homeostasis. Int J Mol Sci. 2023;24: pubmed publisher
Barsheshet Y, Wildbaum G, Levy E, Vitenshtein A, Akinseye C, Griggs J, et al. CCR8+FOXp3+ Treg cells as master drivers of immune regulation. Proc Natl Acad Sci U S A. 2017;114:6086-6091 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Jang S, Kim Y, Kim Y, Sung H, Ko J. Regulation of human LZIP expression by NF-kappaB and its involvement in monocyte cell migration induced by Lkn-1. J Biol Chem. 2007;282:11092-100 pubmed
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Cappello P, Caorsi C, Bosticardo M, De Angelis S, Novelli F, Forni G, et al. CCL16/LEC powerfully triggers effector and antigen-presenting functions of macrophages and enhances T cell cytotoxicity. J Leukoc Biol. 2004;75:135-42 pubmed

product information

master code :

802-HC

SKU :

802-HC-025

product name :

Recombinant Human CCL16/HCC-4 Protein

unit size :

25 ug

description :

The Recombinant Human CCL16/HCC-4 Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL16/HCC-4 Protein has been validated for the following applications: Bioactivity.

target :

CCL16/HCC-4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

11 kDa

gene symbol :

CCL16

details of functionality :

Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. Hedrick, J. et al . (1998) Blood 91 :4242. The ED50 for this effect is 0.5-2á╡g/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR1. The ED50 for this effect is 0.15-0.75á╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O15467

applications :

Bioactivity

source long :

E. coli -derived human CCL16/HCC-4 protein Gln24-Gln120

source short :

E. coli

USD :

252 USD

alt names :

C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC4, HCC-4, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMC, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC-4, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage