Recombinant Rat TNF RI/TNFRSF1A Fc Chimera Protein, CF | R&D Systems 7990-TR-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat TNF RI/TNFRSF1A Fc Chimera Protein, CF

catalog :

7990-TR-025

quantity :

25 ug

price :

408 USD

citations: 1

Reference
Clark A, Gruber Schoffnegger D, Drdla Schutting R, Gerhold K, Malcangio M, SandkÃ¼hler J. Selective activation of microglia facilitates synaptic strength. J Neurosci. 2015;35:4552-70 pubmed publisher

product information

master code :

7990-TR

SKU :

7990-TR-025

product name :

Recombinant Rat TNF RI/TNFRSF1A Fc Chimera Protein, CF

unit size :

25 ug

description :

The Recombinant Rat TNF RI/TNFRSF1A Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat TNF RI/TNFRSF1A Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TNF RI/TNFRSF1A

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE with silver staining

species :

Rat

observed molecular weight :

60-65 kDa, reducing conditions

theoretical molecular weight :

47.3 kDa (monomer)

gene symbol :

Tnfrsf1a

details of functionality :

Measured by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews,áN. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 0.5-3 ng/mL in the presence of 0.1 ng/mL of Recombinant Rat TNF-alpha (Catalog # 510-RT ).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P22934

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived rat TNF RI/TNFRSF1A protein Rat TNF RI/TNFRSF1A (Leu30-Ala211) Accession # P22934 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus

source short :

NS0

USD :

408 USD

alt names :

CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.