Recombinant Mouse Integrin alpha M beta 2 Protein, CF | R&D Systems 7959-AM-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Integrin alpha M beta 2 Protein, CF

catalog :

7959-AM-050

quantity :

50 ug

price :

509 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Takeda K, Kaifu T, Michihata R, Kinugawa N, Fujioka A, Tateno A, et al. Chronic encephalomyelitis virus exhibits cellular tropism and evades pDCs by binding to sialylated integrins as the cell surface receptors. Eur J Immunol. 2023;53:e2350452 pubmed publisher
Ueno K, Otani Y, Yanagihara N, Urai M, Nagamori A, Sato Fukushima M, et al. Cryptococcus gattii evades CD11b-mediated fungal recognition by coating itself with capsular polysaccharides. Eur J Immunol. 2021;51:2281-2295 pubmed publisher
Wang X, Gray M, Hewlett E, Maynard J. The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. J Biol Chem. 2015;290:3576-91 pubmed publisher

product information

master code :

7959-AM

SKU :

7959-AM-050

product name :

Recombinant Mouse Integrin alpha M beta 2 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Integrin alpha M beta 2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Integrin alpha M beta 2 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha M beta 2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE with silver staining

species :

Mouse

observed molecular weight :

155-180 kDa 95-105 kDa, reducing conditions

theoretical molecular weight :

130 kDa (Integrin alpha M) 83 kDa (Integrin ▀2)

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with ICAM-1. The ED50 for this effect is 0.4-1.6 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_032427 (Integrin alpha M) P11835 (Integrin ▀2)

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived mouse Integrin alpha M beta 2 protein Mouse Integrin alpha M (Phe17-Asn1105) Accession # NP_032427 His-Pro GGGSGGGS Acidic Tail 6-His tag Mouse Integrin ▀2 (Gln24-Asn702) Accession # P11835 His-Pro GGGSGGGS Basic Tail N-terminus C-terminus

source short :

CHO

USD :

509 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage