Recombinant Mouse IL-17A (CHO-expressed) Protein | R&D Systems 7956-ML-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-17A (CHO-expressed) Protein

catalog :

7956-ML-025

quantity :

25 ug

price :

300 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Lv X, Lv S, Wang G, Chang Y, Cai Y, Liu H, et al. Glia-derived adenosine in the ventral hippocampus drives pain-related anxiodepression in a mouse model resembling trigeminal neuralgia. Brain Behav Immun. 2024;117:224-241 pubmed publisher
Wayne C, Bremner L, Faust T, Dur xe1 n Laforet V, Ampatey N, Ho S, et al. Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis. bioRxiv. 2023;: pubmed publisher
Knizkova D, Pribikova M, Draberova H, Semberova T, Trivic T, Synackova A, et al. CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology. Nat Immunol. 2022;23:1644-1652 pubmed publisher
Byrne E, Llorián Salvador M, Tang M, Margariti A, Chen M, Xu H. IL-17A Damages the Blood-Retinal Barrier through Activating the Janus Kinase 1 Pathway. Biomedicines. 2021;9: pubmed publisher
Wang Y, Gao S, Gao S, Li N, Xie B, Shen X. Blocking the interaction between interleukin-17A and endoplasmic reticulum stress in macrophage attenuates retinal neovascularization in oxygen-induced retinopathy. Cell Biosci. 2021;11:82 pubmed publisher

product information

brand :

R&D Systems

master code :

7956-ML

SKU :

7956-ML-025

product name :

Recombinant Mouse IL-17A (CHO-expressed) Protein

unit size :

25 ug

seo description :

The Recombinant Mouse IL-17A (CHO-expressed) Protein from R&D Systems is derived from CHO. The Recombinant Mouse IL-17A (CHO-expressed) Protein has been validated for the following applications: Bioactivity.

target :

IL-17/IL-17A

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

15 -22 kDa, reducing conditions

theoretical molecular weight :

15 kDa (monomer)

gene symbol :

Il17a

details of functionality :

Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.25-1.25 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q62386

applications :

Bioactivity

source :

CHO-derived Recombinant Mouse IL-17A (CHO-expressed) Protein

USD :

300 USD

alt names :

CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage