product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human GM-CSF (CHO-expressed) Protein
catalog :
7954-GM-010
quantity :
10 ug
price :
276 USD
more info or order :
R&D Systems product webpage
citations: 9
Reference
Ben Crentsil N, Mohammed Ismail W, Balasis M, Newman H, Quintana A, Binder M, et al. RNA Shielding of p65 Is Required to Potentiate Oncogenic Inflammation in TET2-Mutated Clonal Hematopoiesis. Cancer Discov. 2024;14:2509-2531 pubmed publisher
Huang B, Coventry B, Borowska M, Arhontoulis D, Exposit M, Abedi M, et al. De novo design of miniprotein antagonists of cytokine storm inducers. Nat Commun. 2024;15:7064 pubmed publisher
Moore K, Pelletier A, Lapp S, Metz A, Tharp G, Lee M, et al. Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells. bioRxiv. 2024;: pubmed publisher
Martins C, Rasbach E, Heppt M, Singh P, Kulcsar Z, Holzgruber J, et al. Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling. Sci Adv. 2024;10:eadi2012 pubmed publisher
Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, et al. TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer. Cancers (Basel). 2023;15: pubmed publisher
Pan H, Guo J, Zhu L, Leung S, Zhang C, Lam J. Enhanced powder dispersion of dual-excipient spray-dried powder formulations of a monoclonal antibody and its fragment for local treatment of severe asthma. Int J Pharm. 2023;644:123272 pubmed publisher
Wang X, Cooper S, Broxmeyer H, Kapur R. Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment. Leukemia. 2023;37:453-464 pubmed publisher
Zhu J, Chen Z, Peng X, Zheng Z, Le A, Guo J, et al. Extracellular Vesicle-Derived circITGB1 Regulates Dendritic Cell Maturation and Cardiac Inflammation via miR-342-3p/NFAM1. Oxid Med Cell Longev. 2022;2022:8392313 pubmed publisher
Medelin M, Giacco V, Aldinucci A, Castronovo G, Bonechi E, Sibilla A, et al. Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro. Mol Brain. 2018;11:3 pubmed publisher
product information
master code :
7954-GM
SKU :
7954-GM-010
product name :
Recombinant Human GM-CSF (CHO-expressed) Protein
unit size :
10 ug
description :
The Recombinant Human GM-CSF (CHO-expressed) Protein from R&D Systems is derived from CHO. The Recombinant Human GM-CSF (CHO-expressed) Protein has been validated for the following applications: Bioactivity.
target :
GM-CSF
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
20-35 kDa, reducing conditions
theoretical molecular weight :
14.5 kDa
gene symbol :
CSF2
details of functionality :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 6-30 pg/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P04141
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human GM-CSF protein Ala18-Glu144
source short :
CHO
extended description :
Analyzed by SEC-MALS
USD :
276 USD
product details :
Analyzed by SEC-MALS
alt names :
colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, CSF2, CSF-2, GMCSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, Molgramostim, molgramostin, sargramostim
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.