product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human LRG1 Protein, CF
catalog :
7890-LR-025
quantity :
25 ug
price :
432 USD
more info or order :
citations: 6
Reference
Grzesiak L, Amaya Garrido A, Feuillet G, Malet N, Swiader A, Sarthou M, et al. Leucine-Rich Alpha-2 Glycoprotein 1 Accumulates in Complicated Atherosclerosis and Promotes Calcification. Int J Mol Sci. 2023;24: pubmed publisher
Patel S, Sparman N, Arneson D, Alvarsson A, Santos L, Duesman S, et al. Mammary duct luminal epithelium controls adipocyte thermogenic programme. Nature. 2023;620:192-199 pubmed publisher
Choi C, Barr W, Zaman S, Model C, Park A, Koenen M, et al. LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation. elife. 2022;11: pubmed publisher
Ho C, Zheng D, Sun J, Wen D, Wu S, Yu L, et al. LRG-1 promotes fat graft survival through the RAB31-mediated inhibition of hypoxia-induced apoptosis. J Cell Mol Med. 2022;26:3153-3168 pubmed publisher
Kim H, Kang K, Shin Y, Byun Y, Han Y, Kwon W, et al. Biomarker Panel for the Diagnosis of Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2020;12: pubmed publisher
Zhang J, Zhu L, Fang J, Ge Z, Li X. LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation. J Exp Clin Cancer Res. 2016;35:29 pubmed publisher
product information
master code :
7890-LR
SKU :
7890-LR-025
product name :
Recombinant Human LRG1 Protein, CF
unit size :
25 ug
description :
The Recombinant Human LRG1 Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human LRG1 Protein, CF has been validated for the following applications: Bioactivity.
target :
LRG1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
40-60 kDa, reducing conditions
theoretical molecular weight :
35.2 kDa
gene symbol :
LRG1
details of functionality :
Measured by its binding ability in a functional ELISA. When human Cytochrome c is coated at 1 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human LRG1 that produces 50% of the optimal binding response is 3-15 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P02750
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived human LRG1 protein Val36-Gln347, with a C-terminal 6-His tag
source short :
HEK293
USD :
432 USD
alt names :
1300008B03Rik, 2310031E04Rik, HMFT1766, leucine-rich alpha-2-glycoprotein, leucine-rich alpha-2-glycoprotein 1, LRGleucine rich alpha 2 glycoprotein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.