Recombinant Mouse Integrin alpha V beta 3 Protein, CF | R&D Systems 7889-AV-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Integrin alpha V beta 3 Protein, CF

catalog :

7889-AV-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Zhang S, Tamura A, Yui N. Enhanced Tumor Targeting and Antitumor Activity of Methylated β-Cyclodextrin-Threaded Polyrotaxanes by Conjugating Cyclic RGD Peptides. Biomolecules. 2024;14: pubmed publisher
Bieri M, Hendrickx R, Bauer M, Yu B, Jetzer T, Dreier B, et al. The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection. PLoS Pathog. 2021;17:e1010083 pubmed publisher
Koh K, Cao Y, Mangos S, Tardi N, Dande R, Lee H, et al. Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist. J Clin Invest. 2019;129:1713-1726 pubmed publisher
Negishi Y, Hamano N, Sato H, Katagiri F, Takatori K, Endo Takahashi Y, et al. Development of a Screening System for Targeting Carriers Using Peptide-Modified Liposomes and Tissue Sections. Biol Pharm Bull. 2018;41:1107-1111 pubmed publisher

product information

brand :

R&D Systems

master code :

7889-AV

SKU :

7889-AV-050

product name :

Recombinant Mouse Integrin alpha V beta 3 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse Integrin alpha V beta 3 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Integrin alpha V beta 3 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha V beta 3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE with silver staining

species :

Mouse

observed molecular weight :

135-145 kDa 100-115 kDa, reducing conditions

theoretical molecular weight :

115 kDa (Integrin alpha V) 84.5 kDa (Integrin ▀3)

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Vitronectin (Catalog # 2308-VN ) at 1 ╡g/mL can bind Recombinant Mouse Integrin alpha V▀3 with an apparent KD 5 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P43406 (Integrin alpha V) O54890 (Integrin ▀3)

applications :

Bioactivity

source :

CHO-derived Recombinant Mouse Integrin alpha V beta 3 Protein, CF

USD :

432 USD

alt names :

antigen identified by monoclonal L230, CD51, CD51 antigen, integrin alpha-V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), MSK8, Vitronectin receptor subunit alpha, VNRADKFZp686A08142

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage