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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Thrombospondin-1 Protein, CF
catalog :
7859-TH-050
quantity :
50 ug
price :
509 USD
more info or order :
R&D Systems product webpage
citations: 12
Reference
Wilson Z, Raya Sandino A, Miranda J, Fan S, Brazil J, Quirós M, et al. Critical role of thrombospondin-1 in promoting intestinal mucosal wound repair. JCI Insight. 2024;9: pubmed publisher
Andries L, Kancheva D, Masin L, Scheyltjens I, Van Hove H, De Vlaminck K, et al. Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons. Acta Neuropathol Commun. 2023;11:85 pubmed publisher
Southerland K, Xu Y, Peters D, Wei X, Lin X, Xiang Y, et al. Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cells. bioRxiv. 2023;: pubmed publisher
Jacquemin G, Wurmser A, Huyghe M, Sun W, Homayed Z, Merle C, et al. Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme. elife. 2022;11: pubmed publisher
He C, Jiang B, Wang M, Ren P, Murtada S, Caulk A, et al. mTOR inhibition prevents angiotensin II-induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice. JCI Insight. 2022;7: pubmed publisher
Jeanne A, Sarazin T, Charlé M, Moali C, Fichel C, Boulagnon Rombi C, et al. Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity. Cancers (Basel). 2021;13: pubmed publisher
Conart J, Blot G, Augustin S, Millet Puel G, Roubeix C, Beguier F, et al. Insulin inhibits inflammation-induced cone death in retinal detachment. J Neuroinflammation. 2020;17:358 pubmed publisher
Cartee N, Wang M. Binding of omeprazole to protein targets identified by monoclonal antibodies. PLoS ONE. 2020;15:e0239464 pubmed publisher
Wang F, Liu Y, Zhang T, Gao J, Xu Y, Xie G, et al. Aging-associated changes in CD47 arrangement and interaction with thrombospondin-1 on red blood cells visualized by super-resolution imaging. Aging Cell. 2020;19:e13224 pubmed publisher
Liu Z, Jiang Y, Li X, Hu Z. Embryonic Stem Cell-Derived Peripheral Auditory Neurons Form Neural Connections with Mouse Central Auditory Neurons In Vitro via the ?2?1 Receptor. Stem Cell Reports. 2018;11:157-170 pubmed publisher
Gao Q, Chen K, Gao L, Zheng Y, Yang Y. Thrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells. Cell Death Dis. 2016;7:e2368 pubmed publisher
Zheng Y, Zou F, Wang J, Yin G, Le V, Fei Z, et al. Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein. J Biol Chem. 2015;290:8975-86 pubmed publisher
product information
brand :
R&D Systems
master code :
7859-TH
SKU :
7859-TH-050
product name :
Recombinant Mouse Thrombospondin-1 Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse Thrombospondin-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Thrombospondin-1 Protein, CF has been validated for the following applications: Bioactivity.
target :
Thrombospondin-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
130-155 kDa, reducing conditions
theoretical molecular weight :
129 kDa
gene symbol :
Thbs1
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of SVEC4-10 mouse vascular endothelial cells. The ED50 for this effect is 0.1-0.5 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_035710
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Thrombospondin-1 Protein, CF
USD :
509 USD
alt names :
THBS, THBS1, THBS-1, thrombospondin 1, Thrombospondin1, thrombospondin-1p180, TSP-1, TSP1thrombospondin-1, TSPTSP-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.