Recombinant Human Endosialin/CD248 Protein, CF | R&D Systems 7855-CD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Endosialin/CD248 Protein, CF

catalog :

7855-CD-050

quantity :

50 ug

price :

567 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Pai C, Lin S, Liu C, Pan S, Hsu H, Chen Y, et al. Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis. Sci Rep. 2020;10:16772 pubmed publisher
Capone E, Piccolo E, Fichera I, Ciufici P, Barcaroli D, Sala A, et al. Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma. Oncotarget. 2017;8:60368-60377 pubmed publisher

product information

master code :

7855-CD

SKU :

7855-CD-050

product name :

Recombinant Human Endosialin/CD248 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Endosialin/CD248 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Endosialin/CD248 Protein, CF has been validated for the following applications: Bioactivity.

target :

Endosialin/CD248

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

110-150 kDa, reducing conditions

theoretical molecular weight :

72 kDa

gene symbol :

CD248

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Endosialin/CD248 is immobilized at 2 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human Galectin-3BP/MAC-2BP (Catalog # 2226-GA ) that produces 50% of the optimal binding response is approximately 0.08-0.4 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9HCU0

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Endosialin/CD248 protein Gln18-Arg685, with a C-terminal 6-His tag

source short :

NS0

USD :

567 USD

alt names :

2610111G01Rik, CD164 sialomucin-like 1, CD164L1, CD248, CD248 antigen, CD248 antigen, endosialin, CD248 molecule, endosialin, endosialin, MGC119479, TEM1, TEM1MGC119478, Tumor endothelial marker 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage