Recombinant Mouse Common gamma Chain Fc Chimera Protein, CF | R&D Systems 784-MR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Common gamma Chain Fc Chimera Protein, CF

catalog :

784-MR-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Chun J, Lim B, Roy S, Walsh M, Abhiraman G, Zhangxu K, et al. Potent antitumor activity of a designed interleukin-21 mimic. bioRxiv. 2024;: pubmed publisher

product information

master code :

784-MR

SKU :

784-MR-050

product name :

Recombinant Mouse Common gamma Chain Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Common gamma Chain Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse Common gamma Chain Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Common gamma Chain/IL-2 R gamma

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

60 kDa, reducing conditions

theoretical molecular weight :

54.5 kDa (monomer)

gene symbol :

Il2rg

details of functionality :

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 2-10 ╡g/mL in the presence of 30 ╡g/mL of soluble IL-2 R▀ and 10 ng/mL of recombinant human IL-2.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q3UPA9

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse Common gamma Chain/IL-2 R gamma protein Mouse Common gamma Chain (Ser25-Ala263) Accession # Q3UPA9 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

Sf 21 (baculovirus)

USD :

432 USD

alt names :

CD132, CD132 antigen, CIDX, combined immunodeficiency, X-linked, common cytokine receptor gamma chain, common gamma-chain, cytokine receptor common subunit gamma, gamma(c), IL-2 R gamma, IL-2 receptor subunit gamma, IL2R gamma, IL-2R subunit gamma, IL2RG, IL-2RG, IMD4, interleukin 2 receptor, gamma, Interleukin-2 receptor subunit gamma, p64, SCIDX, SCIDX1, severe combined immunodeficiency

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage