Recombinant Human Integrin alpha 6 beta 1 Protein, CF | R&D Systems 7809-A6 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha 6 beta 1 Protein, CF

catalog :

7809-A6

quantity :

50 ug

price :

369 USD

citations: 3

Reference
Rajan A, Persson B, Frängsmyr L, Olofsson A, Sandblad L, Heino J, et al. Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018;8:10019 pubmed publisher
Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I, Patarroyo M. Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins. Matrix Biol. 2014;36:5-14 pubmed publisher
Stampolidis P, Ullrich A, Iacobelli S. LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention. Oncogene. 2015;34:39-52 pubmed publisher

product information

brand :

R&D Systems

master code :

7809-A6

SKU :

7809-A6-050

product name :

Recombinant Human Integrin alpha 6 beta 1 Protein, CF

description :

The Recombinant Human Integrin alpha 6 beta 1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 6 beta 1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha 6 beta 1

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

110-140 kDa 140 - 170 kDa, reducing conditions

theoretical molecular weight :

119 kDa ( alpha 6 subunit) 86.4 kDa ( beta 1 subunit)

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Laminin alpha 4 (Catalog # 7340-A4 ) is coated at 5 µg/mL, Recombinant Human Integrin alpha 6 beta 1 binds with apparent KD 2nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

7809-A6

accessionNumbers :

NP_000201 ( alpha 6 subunit) P05556 ( beta 1 subunit)

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha 6 beta 1 protein Human Integrin alpha 6 (Phe24-Ser1012) Accession # NP_000201 GGGSGGGS Acidic Tail HHHHHH Human Integrin beta 1 (Gln21-Asp728) Accession # P05556 GGGSGGGS Basic Tail N-terminus C-terminus

2020 USD :

369

2021 USD :

369 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.