Recombinant Human Integrin alpha 6 beta 1 Protein, CF | R&D Systems 7809-A6-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha 6 beta 1 Protein, CF

catalog :

7809-A6-050

quantity :

50 ug

price :

468 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Rajan A, Persson B, Frängsmyr L, Olofsson A, Sandblad L, Heino J, et al. Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018;8:10019 pubmed publisher
Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I, Patarroyo M. Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins. Matrix Biol. 2014;36:5-14 pubmed publisher
Stampolidis P, Ullrich A, Iacobelli S. LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention. Oncogene. 2015;34:39-52 pubmed publisher

product information

brand :

R&D Systems

master code :

7809-A6

SKU :

7809-A6-050

product name :

Recombinant Human Integrin alpha 6 beta 1 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human Integrin alpha 6 beta 1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 6 beta 1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha 6 beta 1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

110-140 kDa 140 - 170 kDa, reducing conditions

theoretical molecular weight :

119 kDa ( alpha 6 subunit) 86.4 kDa (▀1 subunit)

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Laminin alpha 4 (Catalog # 7340-A4 ) is coated at 5 ╡g/mL, Recombinant Human Integrin alpha 6▀1 binds with apparent KD 2nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_000201 ( alpha 6 subunit) P05556 (▀1 subunit)

applications :

Bioactivity

source :

CHO-derived Recombinant Human Integrin alpha 6 beta 1 Protein, CF

USD :

468 USD

alt names :

CD49f, ITGA6B, VLA-6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage