Recombinant Human L1CAM Fc Chimera Protein, CF | R&D Systems 777-NC-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human L1CAM Fc Chimera Protein, CF

catalog :

777-NC-100

quantity :

100 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Kim J, Lee K, Ahn D, Oh K, Yoon H. Clinical significance of L1CAM expression and its biological role in the progression of oral squamous cell carcinoma. Oncol Rep. 2023;49: pubmed publisher
Hatayama M, Katayama K, Kawahara Y, Matsunaga H, Takashima N, Iwayama Y, et al. SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex. Commun Biol. 2022;5:935 pubmed publisher
Stromecki M, Tatari N, Morrison L, Kaur R, Zagozewski J, Palidwor G, et al. Characterization of a novel OTX2-driven stem cell program in Group 3 and Group 4 medulloblastoma. Mol Oncol. 2018;12:495-513 pubmed publisher
Tatti O, Gucciardo E, Pekkonen P, Holopainen T, Louhimo R, Repo P, et al. MMP16 Mediates a Proteolytic Switch to Promote Cell-Cell Adhesion, Collagen Alignment, and Lymphatic Invasion in Melanoma. Cancer Res. 2015;75:2083-94 pubmed publisher
Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel M, et al. Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J Neurosci. 2008;28:7624-36 pubmed publisher
Allory Y, Audard V, Fontanges P, Ronco P, Debiec H. The L1 cell adhesion molecule is a potential biomarker of human distal nephron injury in acute tubular necrosis. Kidney Int. 2008;73:751-8 pubmed

product information

master code :

777-NC

SKU :

777-NC-100

product name :

Recombinant Human L1CAM Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Human L1CAM Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human L1CAM Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

L1CAM

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

210-225 kDa, reducing conditions

theoretical molecular weight :

150.4 kDa (monomer) 55.9 kDa (truncated)

gene symbol :

L1CAM

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of Neuro-2A mouse neuroblastoma cells. When 5 x 104 cells/well are added to Recombinant Human L1CAM Fc Chimera coated plates (25 ╡g/mL with 100 ╡L/well), 30% will adhere for 1 hour incubation at 37 ░C. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

CAA42508

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human L1CAM protein Human L1CAM (Ile20-Glu1120) (Arg864-Glu1120) Accession # CAA42508 IEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

antigen identified by monoclonal R1, CAML1, CAML1N-CAML1, CD171, CD171 antigen, HSAS, HSAS1, L1 cell adhesion molecule, MASA, MIC5, N-CAM-L1, NCAM-L1, neural cell adhesion molecule L1, S10, SPG1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 4 weeks, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage