product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse VEGFR1/Flt-1 Fc Chimera Protein, CF
catalog :
7756-FL-050
quantity :
50 ug
price :
456 USD
more info or order :
citations: 4
Reference
Verma M, Asakura Y, Wang X, Zhou K, xdc nverdi M, Kann A, et al. Endothelial cell signature in muscle stem cells validated by VEGFA-FLT1-AKT1 axis promoting survival of muscle stem cell. elife. 2024;13: pubmed publisher
Li R, Wang N, Xue M, Long W, Cheng C, Mi C, et al. A potential regulatory network among WDR86-AS1, miR-10b-3p, and LITAF is possibly involved in preeclampsia pathogenesis. Cell Signal. 2019;55:40-52 pubmed publisher
Beaujean O, Locri F, Aronsson M, Kvanta A, André H. A novel in vivo model of puncture-induced iris neovascularization. PLoS ONE. 2017;12:e0180235 pubmed publisher
Luo L, Uehara H, Zhang X, Das S, Olsen T, Holt D, et al. Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. elife. 2013;2:e00324 pubmed publisher
product information
brand :
R&D Systems
master code :
7756-FL
SKU :
7756-FL-050
product name :
Recombinant Mouse VEGFR1/Flt-1 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse VEGFR1/Flt-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse VEGFR1/Flt-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
VEGFR1/Flt-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
130-150 kDa, reducing conditions
theoretical molecular weight :
109.6 kDa (monomer)
gene symbol :
Flt1
details of functionality :
Measured by its ability to inhibit the VEGF-dependent proliferation of HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 5-30 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P35969
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse VEGFR1/Flt-1 Fc Chimera Protein, CF
USD :
456 USD
alt names :
EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.