product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse ICAM-2/CD102 Fc Chimera Protein, CF
catalog :
774-M2-050
quantity :
50 ug (also 200 ug)
price :
300 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Paetau S, Rolova T, Ning L, Gahmberg C. Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia. Front Mol Neurosci. 2017;10:431 pubmed publisher
Halai K, Whiteford J, Ma B, Nourshargh S, Woodfin A. ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo. J Cell Sci. 2014;127:620-9 pubmed publisher
Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin. J Biol Chem. 2012;287:39041-9 pubmed publisher
product information
master code :
774-M2
SKU :
774-M2-050
product name :
Recombinant Mouse ICAM-2/CD102 Fc Chimera Protein, CF
unit size :
50 ug (also 200 ug)
description :
The Recombinant Mouse ICAM-2/CD102 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse ICAM-2/CD102 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
ICAM-2/CD102
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris, Citric Acid and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
75-80 kDa, reducing conditions
theoretical molecular weight :
49.5 kDa (monomer)
gene symbol :
Icam2
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. Recombinant Mouse ICAM-2/CD102 Fc Chimera immobilized at 12.5 ╡g/mL (100 ╡L/well) will induce 65% cell adhesion. Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P35330
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse ICAM-2/CD102 protein Mouse ICAM-2 (Ser20-Gln222) Accession # P35330 DIEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
300 USD
alt names :
CD102, CD102 antigen, ICAM2, ICAM-2, intercellular adhesion molecule 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.