product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Flt-3/Flk-2 Fc Chimera Protein, CF
catalog :
768-F3-050
quantity :
50 ug
price :
432 USD
more info or order :
citations: 4
Reference
Tassou A, Thouaye M, Gilabert D, Jouvenel A, Leyris J, Sonrier C, et al. Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain. Prog Neurobiol. 2023;222:102405 pubmed publisher
Sakabe I, Asai A, Iijima J, Maruyama M. Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells. Immun Ageing. 2012;9:2 pubmed publisher
Yuan W, Payton J, Holt M, Link D, Watson M, DiPersio J, et al. Commonly dysregulated genes in murine APL cells. Blood. 2007;109:961-70 pubmed
Yilmaz O, Kiel M, Morrison S. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood. 2006;107:924-30 pubmed
product information
brand :
R&D Systems
master code :
768-F3
SKU :
768-F3-050
product name :
Recombinant Mouse Flt-3/Flk-2 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse Flt-3/Flk-2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Flt-3/Flk-2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Flt-3/Flk-2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
116 kDa, reducing conditions
theoretical molecular weight :
85 kDa (monomer)
gene symbol :
Flt3
details of functionality :
Measured by its ability to inhibit Flt-3 Ligand-induced proliferation of BaF3 mouse pro-B cells transfected with Flt-3. The ED50 for this effect is 0.05-0.25 ╡g/mL in the presence of recombinant mouse Flt-3 Ligand at 10 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q00342
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Flt-3/Flk-2 Fc Chimera Protein, CF
USD :
432 USD
alt names :
CD135, CD135 antigen, EC 2.7.10, fetal liver kinase 2, FL cytokine receptor, Flk-2, FLK2, Flt3, FLT-3, FLT3 receptor tyrosine kinase, Fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, STK-1, STK1EC 2.7.10.1, Tyrosine-protein kinase receptor FLT3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.