product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGFR3 (IIIc) Fc Chimera Protein, CF
catalog :
766-FR-050
quantity :
50 ug
price :
400 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Yanucil C, Kentrup D, Li X, Grabner A, Schramm K, Martinez E, et al. FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes. Sci Rep. 2022;12:7326 pubmed publisher
Min B, Yoo M, Kim H, Cho M, Nam D, Yoon Y. Semi-Automated Cell Panning for Efficient Isolation of FGFR3-Targeting Antibody. Int J Mol Sci. 2021;22: pubmed publisher
Chan W, Howe K, Clegg J, Guimond S, Price D, Turnbull J, et al. 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline. PLoS ONE. 2015;10:e0130147 pubmed publisher
Martinez Torrecuadrada J, Cifuentes G, López Serra P, Saenz P, Martinez A, Casal J. Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation. Clin Cancer Res. 2005;11:6280-90 pubmed
product information
brand :
R&D Systems
master code :
766-FR
SKU :
766-FR-050
product name :
Recombinant Human FGFR3 (IIIc) Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human FGFR3 (IIIc) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR3 (IIIc) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR3
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
95-105 kDa, reducing conditions
theoretical molecular weight :
64.7 kDa (monomer)
gene symbol :
FGFR3
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 1-3áng/mL.
endotoxin note :
<0.1 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P22607
applications :
Bioactivity
source :
NS0-derived Recombinant Human FGFR3 (IIIc) Fc Chimera Protein, CF
USD :
400 USD
alt names :
CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.