Recombinant Human Ephrin-B1 Fc Chimera Protein, CF | R&D Systems 7654-EB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Ephrin-B1 Fc Chimera Protein, CF

catalog :

7654-EB-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Vreeken D, Bruikman C, Cox S, Zhang H, Lalai R, Koudijs A, et al. EPH receptor B2 stimulates human monocyte adhesion and migration independently of its EphrinB ligands. J Leukoc Biol. 2020;: pubmed publisher
Wagner M, Hsiung M, Gish G, Bagshaw R, Doodnauth S, Soliman M, et al. The Shb scaffold binds the Nck adaptor protein, p120 RasGAP, and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2. J Biol Chem. 2020;295:3932-3944 pubmed publisher
Cutrale F, Rodriguez D, Hortigüela V, Chiu C, Otterstrom J, Mieruszynski S, et al. Using enhanced number and brightness to measure protein oligomerization dynamics in live cells. Nat Protoc. 2019;14:616-638 pubmed publisher
Arthur A, Nguyen T, Paton S, Klisuric A, Zannettino A, Gronthos S. The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption. Sci Rep. 2018;8:12756 pubmed publisher
Shi X, Sun K, Hu R, Liu X, Hu Q, Sun X, et al. Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease. J Neurosci. 2016;36:11959-11973 pubmed

product information

master code :

7654-EB

SKU :

7654-EB-050

product name :

Recombinant Human Ephrin-B1 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human Ephrin-B1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Ephrin-B1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Ephrin-B1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

62-67 kDa, reducing conditions

theoretical molecular weight :

49.5 kDa (monomer)

gene symbol :

EFNB1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Mouse EphB3 Fc Chimera (Catalog # 432-B3 ) is coated at 2 ╡g/mL, Recombinant Human Ephrin-B1 Fc Chimera binds with an apparent KD 0.2 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P98172

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Ephrin-B1 protein Human Ephrin-B1 (Leu28-Ser236) Accession # P98172 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

Cek5-L, EFL3, EFL-3, EFNB1, ELK ligand, Elk-L, ephrin-B1, EphrinB1, LERK-2, STRA-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage