| Reference |
|---|
Xing Y, Zhang F, Yang T, Yin C, Yang A, Yan B, et al. Augmented antitumor immune responses of HER2-targeted pyroptotic induction by long-lasting recombinant immunopyroptotins. Heliyon. 2024;10:e30444 pubmed publisher |
Wang Y, Chen C, Chen J, Sang T, Peng H, Lin X, et al. Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation. Redox Biol. 2022;52:102322 pubmed publisher |
Bai Y, Han Q, Dong B, Lin H, Jiang Y, Zhang X, et al. PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression. Brain Res Bull. 2022;184:56-67 pubmed publisher |
Lian D, Zhu L, Yu Y, Zhang X, Lin Y, Liu J, et al. Kakonein restores hyperglycemia-induced macrophage digestion dysfunction through regulation of cathepsin B-dependent NLRP3 inflammasome activation. J Leukoc Biol. 2022;112:143-155 pubmed publisher |
Xu P, Tao C, Zhu Y, Wang G, Kong L, Li W, et al. TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage. J Neuroinflammation. 2021;18:188 pubmed publisher |
Igel E, Haller A, Wolfkiel P, Orr Asman M, Jaeschke A, Hui D. Distinct pro-inflammatory properties of myeloid cell-derived apolipoprotein E2 and E4 in atherosclerosis promotion. J Biol Chem. 2021;297:101106 pubmed publisher |
Zhang H, Li X, Wang J, Cheng Q, Shang Y, Wang G. Baicalin relieves Mycoplasma pneumoniae infection‑induced lung injury through regulating microRNA‑221 to inhibit the TLR4/NF‑κB signaling pathway. Mol Med Rep. 2021;24: pubmed publisher |
Cheon S, Koo B, Kim S, Kam E, Nam J, Kim E. Scopolamine promotes neuroinflammation and delirium-like neuropsychiatric disorder in mice. Sci Rep. 2021;11:8376 pubmed publisher |
Ye L, Guo H, Wang Y, Peng Y, Zhang Y, Li S, et al. Exosomal circEhmt1 Released from Hypoxia-Pretreated Pericytes Regulates High Glucose-Induced Microvascular Dysfunction via the NFIA/NLRP3 Pathway. Oxid Med Cell Longev. 2021;2021:8833098 pubmed publisher |
Eissa N, Elgazzar O, Hussein H, Hendy G, Bernstein C, Ghia J. Pancreastatin Reduces Alternatively Activated Macrophages, Disrupts the Epithelial Homeostasis and Aggravates Colonic Inflammation. A Descriptive Analysis. Biomedicines. 2021;9: pubmed publisher |
Wu X, Pan S, Luo W, Shen Z, Meng X, Xiao M, et al. Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis. Mol Med Rep. 2020;22:2695-2704 pubmed publisher |
de la Rosa G, Gómez A, Baños M, Pelegrin P. Signaling Through Purinergic Receptor P2Y2 Enhances Macrophage IL-1β Production. Int J Mol Sci. 2020;21: pubmed publisher |
Xiong S, Hong Z, Huang L, Tsukasaki Y, Nepal S, Di A, et al. IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury. J Clin Invest. 2020;130:3684-3698 pubmed publisher |
Ling L, Zheng D, Zhang Z, Xie W, Huang Y, Chen Z, et al. Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes. Oncol Lett. 2020;19:2861-2869 pubmed publisher |
Lecoeur H, Prina E, Rosazza T, Kokou K, N Diaye P, Aulner N, et al. Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response. Cell Rep. 2020;30:1870-1882.e4 pubmed publisher |
Rumfield C, Hyseni I, McBride J, Walker D, Fang R. Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection. Infect Immun. 2020;88: pubmed publisher |
Wang S, Shao B, Zhao S, Chang X, Wang P, Miao C, et al. Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease. Cell Death Dis. 2019;10:391 pubmed publisher |
Semper R, Vieth M, Gerhard M, Mejías Luque R. Helicobacter pylori Exploits the NLRC4 Inflammasome to Dampen Host Defenses. J Immunol. 2019;203:2183-2193 pubmed publisher |
Chen R, Zeng L, Zhu S, Liu J, Zeh H, Kroemer G, et al. cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis. Sci Adv. 2019;5:eaav5562 pubmed publisher |
Bae J, Jo S, Kim S, Lee J, Jeong J, Kang J, et al. Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes. Cells. 2019;8: pubmed publisher |
Kurundkar D, Kurundkar A, Bone N, Becker E, Liu W, Chacko B, et al. SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury. JCI Insight. 2019;4: pubmed publisher |
Perera A, Fernando R, Shinde T, Gundamaraju R, Southam B, Sohal S, et al. MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice. Sci Rep. 2018;8:8618 pubmed publisher |
Zhu J, Chen L, Qi Y, Feng J, Zhu L, Bai Y, et al. Protective effects of Erigeron breviscapus Hand.- Mazz. (EBHM) extract in retinal neurodegeneration models. Mol Vis. 2018;24:315-325 pubmed |
Kong Y, Xu S. Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis. Oncol Rep. 2018;39:2513-2526 pubmed publisher |
Song H, Li X, Liu Y, Lu W, Cui Z, Zhou L, et al. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS. Int J Mol Med. 2018;42:193-207 pubmed publisher |
Dong Z, Yuan Y. Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury. Int J Mol Med. 2018;41:3353-3365 pubmed publisher |
Su C, Wang I, Liu S, Sun Y, Jin L, Wang S, et al. Hypoxia induced mitogenic factor (HIMF) triggers angiogenesis by increasing interleukin-18 production in myoblasts. Sci Rep. 2017;7:7393 pubmed publisher |
Stier M, Goleniewska K, Cephus J, Newcomb D, Sherrill T, Boyd K, et al. STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection. J Immunol. 2017;199:510-519 pubmed publisher |
Aroor A, Habibi J, Kandikattu H, Garro Kacher M, Barron B, Chen D, et al. Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice. Cardiovasc Diabetol. 2017;16:61 pubmed publisher |
van Gelder M, Vanclée A, Van Elssen C, Hupperets P, Wieten L, Bos G. Bone marrow produces sufficient alloreactive natural killer (NK) cells in vivo to cure mice from subcutaneously and intravascularly injected 4T1 breast cancer. Breast Cancer Res Treat. 2017;161:421-433 pubmed publisher |
Sokolova M, Vinge L, Alfsnes K, Olsen M, Eide L, Kaasbøll O, et al. Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:234-245 pubmed publisher |
Primiano M, Lefker B, Bowman M, Bree A, Hubeau C, Bonin P, et al. Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation. J Immunol. 2016;197:2421-33 pubmed publisher |
Kostadinova E, Chaput C, Gutbier B, Lippmann J, Sander L, Mitchell T, et al. NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence. Sci Rep. 2016;6:30943 pubmed publisher |
Pellegrin M, Aubert J, Bouzourène K, Amstutz C, Mazzolai L. Voluntary Exercise Stabilizes Established Angiotensin II-Dependent Atherosclerosis in Mice through Systemic Anti-Inflammatory Effects. PLoS ONE. 2015;10:e0143536 pubmed publisher |
Li S, Sun R, Chen Y, Wei H, Tian Z. TLR2 limits development of hepatocellular carcinoma by reducing IL18-mediated immunosuppression. Cancer Res. 2015;75:986-95 pubmed publisher |
Moriwaki K, Bertin J, Gough P, Chan F. A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing. J Immunol. 2015;194:1938-44 pubmed publisher |
He W, Yang C, Xia L, Zhao M, Ge R, Huang H, et al. CD4(+) T cells from food allergy model are resistant to TCR-dependent apoptotic induction. Cytokine. 2014;68:32-9 pubmed publisher |
Chow M, Duret H, Andrews D, Faveeuw C, Möller A, Smyth M, et al. Type I NKT-cell-mediated TNF-α is a positive regulator of NLRP3 inflammasome priming. Eur J Immunol. 2014;44:2111-20 pubmed publisher |
Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, et al. TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis. PLoS Pathog. 2013;9:e1003646 pubmed publisher |
Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, et al. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5). J Bone Miner Res. 2013;28:2070-80 pubmed publisher |
Srinivasan G, Aitken J, Zhang B, Carvalho F, Chassaing B, Shashidharamurthy R, et al. Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J Immunol. 2012;189:1911-9 pubmed publisher |
Gottfries J, Melgar S, Michaëlsson E. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease. PLoS ONE. 2012;7:e30005 pubmed publisher |
Ghose P, Ali A, Fang R, Forbes D, Ballard B, Ismail N. The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria. J Immunol. 2011;187:1333-46 pubmed publisher |
Doverhag C, Hedtjarn M, Poirier F, Mallard C, Hagberg H, Karlsson A, et al. Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. Neurobiol Dis. 2010;38:36-46 pubmed publisher |
Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, et al. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature. 2009;460:269-73 pubmed publisher |
Venkatachalam K, Prabhu S, Reddy V, Boylston W, Valente A, Chandrasekar B. Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury. J Biol Chem. 2009;284:7853-65 pubmed publisher |
Kang M, Lee C, Lee J, Dela Cruz C, Chen Z, Enelow R, et al. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest. 2008;118:2771-84 pubmed publisher |
Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, et al. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. Eur J Pharmacol. 2008;590:400-8 pubmed publisher |
Rosenzweig H, Martin T, Planck S, Galster K, Jann M, Davey M, et al. Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling. J Leukoc Biol. 2008;84:529-36 pubmed publisher |
Vijay Kumar M, Sanders C, Taylor R, Kumar A, Aitken J, Sitaraman S, et al. Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest. 2007;117:3909-21 pubmed |
Kang M, Homer R, Gallo A, Lee C, Crothers K, Cho S, et al. IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J Immunol. 2007;178:1948-59 pubmed |
Thakur A, Barrett R, McClellan S, Hazlett L. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice. Curr Eye Res. 2004;29:225-33 pubmed |
Verdrengh M, Thomas J, Hultgren O. IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection. Microbes Infect. 2004;6:1268-72 pubmed |
Harandi A, Eriksson K, Holmgren J. A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection. J Virol. 2003;77:953-62 pubmed |
