Recombinant Mouse Tie-2 Fc Chimera Protein, CF | R&D Systems 762-T2-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Tie-2 Fc Chimera Protein, CF

catalog :

762-T2-100

quantity :

100 ug

price :

456 USD

citations: 6

Reference
Paredes I, Vieira J, Shah B, Ramunno C, Dyckow J, Adler H, et al. Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk. Nat Neurosci. 2021;24:478-488 pubmed publisher
Helaine C, Ferré A, Leblond M, Pérès E, Bernaudin M, Valable S, et al. Angiopoietin-2 Combined with Radiochemotherapy Impedes Glioblastoma Recurrence by Acting in an Autocrine and Paracrine Manner: A Preclinical Study. Cancers (Basel). 2020;12: pubmed publisher
Yin G, Jin H, Choi M, Limanjaya A, Ghatak K, Minh N, et al. Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway. Diabetes. 2018;67:1149-1161 pubmed publisher
Gutbier B, Jiang X, Dietert K, Ehrler C, Lienau J, Van Slyke P, et al. Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia. Crit Care. 2017;21:274 pubmed publisher
Yin G, Choi M, Kim W, Kwon M, Song K, Park J, et al. Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse. Proc Natl Acad Sci U S A. 2014;111:E2731-40 pubmed publisher
Popkov M, Jendreyko N, McGavern D, Rader C, Barbas C. Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody. Cancer Res. 2005;65:972-81 pubmed

product information

master code :

762-T2

SKU :

762-T2-100

product name :

Recombinant Mouse Tie-2 Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse Tie-2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Tie-2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

Tie-2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

125-135 kDa, reducing conditions

theoretical molecular weight :

107.2 kDa (monomer)

gene symbol :

Tek

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmTie-2/Fc Chimera at 4á╡g/mL (100á╡L/well) can bind rhAngiopoietin-2 with a linear range of 2-50áng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

CAA47857

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Tie-2 protein Mouse Tie-2 (Ala23 - Lys744) Accession # CAA47857 DIEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.