Recombinant Mouse CCL20/MIP-3 alpha Protein | R&D Systems 760-M3-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CCL20/MIP-3 alpha Protein

catalog :

760-M3-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 14

Reference
Maria Z, Turner E, Agasing A, Kumar G, Axtell R. Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE. Int J Mol Sci. 2021;22: pubmed publisher
Luo K, Gordy J, Zavala F, Markham R. A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques. Sci Rep. 2021;11:1220 pubmed publisher
Da Silva C, Camps M, Li T, Zerrillo L, Löwik C, Ossendorp F, et al. Effective chemoimmunotherapy by co-delivery of doxorubicin and immune adjuvants in biodegradable nanoparticles. Theranostics. 2019;9:6485-6500 pubmed publisher
Wilson A, Law H, Knobbe Thomsen C, Kearney C, Oliaro J, Binsfeld C, et al. Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery. Eur J Immunol. 2019;49:770-781 pubmed publisher
Porras G, Ayuso M, González Manchón C. Leukocyte-endothelial cell interaction is enhanced in podocalyxin-deficient mice. Int J Biochem Cell Biol. 2018;99:72-79 pubmed publisher
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
Huang S, Walker C, Pennock J, Else K, Muller W, Daniels M, et al. P2X7 receptor-dependent tuning of gut epithelial responses to infection. Immunol Cell Biol. 2017;95:178-188 pubmed publisher
Geherin S, GÃ³mez D, Glabman R, Ruthel G, Hamann A, Debes G. IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require Î±4Î²1 Integrin To Migrate between the Peritoneum and Inflamed Skin. J Immunol. 2016;196:2514-2525 pubmed publisher
Badr G, Sayed A, Abdel Maksoud M, Mohamed A, El Amir A, Abdel Ghaffar F, et al. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFÎºB and ERK. PLoS ONE. 2015;10:e0125340 pubmed publisher
Klein M, Brouwer M, Angele B, Geldhoff M, Marquez G, Varona R, et al. Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis. PLoS ONE. 2014;9:e93057 pubmed publisher
Costa M, Bornstein V, Candéa A, Henriques Pons A, Henriques M, Penido C. CCL25 induces ???? integrin-dependent migration of IL-17? ?? T lymphocytes during an allergic reaction. Eur J Immunol. 2012;42:1250-60 pubmed publisher
Cha H, Ko H, Kim E, Chang S, Seo S, Cuburu N, et al. Mucosa-associated epithelial chemokine/CCL28 expression in the uterus attracts CCR10+ IgA plasma cells following mucosal vaccination via estrogen control. J Immunol. 2011;187:3044-52 pubmed publisher
Kotarsky K, Sitnik K, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, et al. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Mucosal Immunol. 2010;3:40-8 pubmed publisher
Ambrosini E, Columba Cabezas S, Serafini B, Muscella A, Aloisi F. Astrocytes are the major intracerebral source of macrophage inflammatory protein-3alpha/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro. Glia. 2003;41:290-300 pubmed

product information

brand :

R&D Systems

master code :

760-M3

SKU :

760-M3-025

product name :

Recombinant Mouse CCL20/MIP-3 alpha Protein

unit size :

25 ug

seo description :

The Recombinant Mouse CCL20/MIP-3 alpha Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CCL20/MIP-3 alpha Protein has been validated for the following applications: Bioactivity.

target :

CCL20/MIP-3 alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

theoretical molecular weight :

7.9 kDa

gene symbol :

Ccl20

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR6. The ED50 for the chemotactic effect is 2-6áng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q642U4

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse CCL20/MIP-3 alpha Protein

USD :

432 USD

alt names :

beta chemokine exodus-1, Beta-chemokine exodus-1, CC chemokine LARC, C-C motif chemokine 20, chemokine (C-C motif) ligand 20, CKb4, exodus-1, LARC, LARCLiver and activation-regulated chemokine, MIP3 alpha, MIP-3 alpha, MIP-3a, MIP-3-alpha, MIP3AMacrophage inflammatory protein 3 alpha, SCYA20Small-inducible cytokine A20, small inducible cytokine subfamily A (Cys-Cys), member 20, ST38

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage