Recombinant Human VEGF-B 167 Protein, CF | R&D Systems 751-VEB-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human VEGF-B 167 Protein, CF

catalog :

751-VEB-025

quantity :

25 ug

price :

400 USD

citations: 10

Reference
Holm A, Graus M, Wylie Sears J, Borgelt L, Heng Tan J, Nasim S, et al. An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma. bioRxiv. 2024;: pubmed publisher
Moon S, Kim H, Kim J, Kim J, Choi J, Won S, et al. An examination of the mechanisms driving the therapeutic effects of an AAV expressing a soluble variant of VEGF receptor-1. PLoS ONE. 2024;19:e0305466 pubmed publisher
Jia J, Zhu X, Xue K, Huang Y, Wu M, Yang Y, et al. LncRNA DANCR Enhances Angiogenesis to Promote Melanoma Progression Via Sponging miR-5194. J Cancer. 2023;14:1161-1173 pubmed publisher
Wu L, Meoli C, Mangiafico S, Fazakerley D, Cogger V, Mohamad M, et al. Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction. Diabetes. 2014;63:2656-67 pubmed publisher
Brave S, Eberlein C, Shibuya M, Wedge S, Barry S. Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model. Angiogenesis. 2010;13:337-47 pubmed publisher
Martino M, Hubbell J. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. FASEB J. 2010;24:4711-21 pubmed publisher
Nilsson M, Zage P, Zeng L, Xu L, Cascone T, Wu H, et al. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. Oncogene. 2010;29:2938-49 pubmed publisher
Ponticelli S, Marasco D, Tarallo V, Albuquerque R, Mitola S, Takeda A, et al. Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1. J Biol Chem. 2008;283:34250-9 pubmed publisher
Narazaki M, Tosato G. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood. 2006;107:3892-901 pubmed
Silvestre J, Tamarat R, Ebrahimian T, Le Roux A, Clergue M, Emmanuel F, et al. Vascular endothelial growth factor-B promotes in vivo angiogenesis. Circ Res. 2003;93:114-23 pubmed

product information

master code :

751-VEB

SKU :

751-VEB-025

product name :

Recombinant Human VEGF-B 167 Protein, CF

unit size :

25 ug

description :

The Recombinant Human VEGF-B 167 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human VEGF-B 167 Protein, CF has been validated for the following applications: Bioactivity.

target :

VEGF-B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HCl with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

19-22 kDa, under reducing conditions

theoretical molecular weight :

19 kDa (monomer)

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Rat Neuropilin-1 Fc Chimera (Catalog # 566-N1 ) is immobilized at 1 ╡g/mL (100 ╡L/well), Recombinant Human VEGF-B 167 (Catalog # 751-VEB) binds with an ED50 of 10-80 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human VEGF-B 167 Protein Binding Activity

accessionNumbers :

AAA91463

applications :

Bioactivity

source long :

E. coli -derived human VEGF-B protein Pro22-Arg188

source short :

E. coli

USD :

400 USD

alt names :

vascular endothelial growth factor B, VEGFB, VEGF-B, VEGF-related factor, VRFVEGFL

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.