product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human SPINK1 Protein, CF
catalog :
7496-PI-010
quantity :
10 ug
price :
541 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Luo D, Liu D, Rao C, Shi S, Zeng X, Liu S, et al. Raised SPINK1 levels play a role in angiogenesis and the transendothelial migration of ALL cells. Sci Rep. 2022;12:2999 pubmed publisher
Kim K, Turner R, Khazan N, Kodza A, Jones A, Singh R, et al. Role of trypsin and protease-activated receptor-2 in ovarian cancer. PLoS ONE. 2020;15:e0232253 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
7496-PI
SKU :
7496-PI-010
product name :
Recombinant Human SPINK1 Protein, CF
description :
The Recombinant Human SPINK1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human SPINK1 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
SPINK1
unit size :
10 ug
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 µm filtered solution in MES, NaCl, CaCl2, DTT, Glycerol and Brij-35.
conjugate :
Unconjugated
purity :
>85%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
observed molecular weight :
8-11 kDa, reducing conditions
theoretical molecular weight :
7 kDa
gene symbol :
SPINK1
details of functionality :
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The IC50 value is 10 nM, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P00995
applications :
Enzyme Activity
product keywords :
7496-PI, rhSPINK1, hSPINK1, carrier-free, carrier free, 7496PI, SPINK 1, Tumor Associated Trypsin inhibitor, Kazal-like Protease Inhibitor, pancreatic acinar cells, pancreas, pancreatic duct, pancreatitis, tropical calcific pancreatitis, fibrocalculous pancreatic diabetes, FCPD, pancreatic cancer, ovarian cancer, bla
source :
E. coli-derived Recombinant Human SPINK1 Protein, CF
USD :
525
USD 2025 :
541 USD
alt names :
pancreatic secretory trypsin inhibitor, PCTT, PCTTSpink3, PSTI, PSTISerine protease inhibitor Kazal-type 1, serine peptidase inhibitor, Kazal type 1, serine protease inhibitor, Kazal type 1, Spink3, TATI, TATITumor-associated trypsin inhibitor
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.