Recombinant Human LIFR alpha (Mammalian-expressed), CF | R&D Systems 7487-LR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human LIFR alpha (Mammalian-expressed), CF

catalog :

7487-LR-050

quantity :

50 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Salm F, Dimitrova V, von Bueren A, Ä†wiek P, Rehrauer H, Djonov V, et al. The Phosphoinositide 3-Kinase p110Î± Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma. PLoS ONE. 2015;10:e0123958 pubmed publisher

product information

master code :

7487-LR

SKU :

7487-LR-050

product name :

Recombinant Human LIFR alpha (Mammalian-expressed), CF

unit size :

50 ug

description :

The Recombinant Human LIFR alpha (Mammalian-expressed), CF from R&D Systems is derived from HEK293. The Recombinant Human LIFR alpha (Mammalian-expressed), CF has been validated for the following applications: Bioactivity.

target :

LIFR alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

110-140 kDa, reducing conditions

theoretical molecular weight :

89.4 kDa

gene symbol :

LIFR

details of functionality :

Measured by its ability to inhibit LIF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is typically 1-6 ╡g/mL in the presence of 0.3 ng/mL of recombinant human LIF.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001121143

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived human LIF R alpha protein Met1-Ser833

source short :

HEK293

USD :

443 USD

alt names :

CD118, CD118 antigen, FLJ98106, FLJ99923, leukemia inhibitory factor receptor, leukemia inhibitory factor receptor alpha, LIF R alpha, LIF R beta, LIF receptor, LIFR, LIF-R, LIFRa, SJS2, STWS, SWS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage