product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human LIFR alpha (Mammalian-expressed), CF
catalog :
7487-LR-050
quantity :
50 ug
price :
443 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Salm F, Dimitrova V, von Bueren A, Ćwiek P, Rehrauer H, Djonov V, et al. The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma. PLoS ONE. 2015;10:e0123958 pubmed publisher
product information
brand :
R&D Systems
catalog number base :
7487-LR
SKU :
7487-LR-050
product name :
Recombinant Human LIFR alpha (Mammalian-expressed), CF
units size :
50 ug
description :
The Recombinant Human LIFR alpha (Mammalian-expressed), CF from R&D Systems is derived from HEK293. The Recombinant Human LIFR alpha (Mammalian-expressed), CF has been validated for the following applications: Bioactivity.
target :
LIFR alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
110-140 kDa, reducing conditions
theoretical molecular weight :
89.4 kDa
gene symbol :
LIFR
details of functionality :
Measured by its ability to inhibit LIF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is typically 1-6 µg/mL in the presence of 0.3 ng/mL of recombinant human LIF.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_001121143
applications :
Bioactivity
source :
HEK293-derived Recombinant Human LIFR alpha (Mammalian-expressed), CF
USD :
443 USD
alt names :
CD118, CD118 antigen, FLJ98106, FLJ99923, leukemia inhibitory factor receptor, leukemia inhibitory factor receptor alpha, LIF R alpha, LIF R beta, LIF receptor, LIFR, LIF-R, LIFRa, SJS2, STWS, SWS
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.