product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-12 R beta 2 Fc Chimera Protein, CF
catalog :
7406-MR-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Georgy J, Arlt Y, Moll J, Ouzin M, Weitz H, Gremer L, et al. Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction. J Biol Chem. 2021;297:101295 pubmed publisher
product information
master code :
7406-MR
SKU :
7406-MR-050
product name :
Recombinant Mouse IL-12 R beta 2 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse IL-12 R beta 2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse IL-12 R beta 2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-12 R beta 2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
125-145 kDa, reducing conditions
theoretical molecular weight :
95.7 kDa (monomer)
gene symbol :
Il12rb2
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Mouse (rm) IL-12 R▀2 Fc Chimera is immobilized at 0.5 ╡g/mL (100 ╡L/well), the concentration of rmIL-12 that produces 50% of the optimal binding response is found to be approximately 4 - 20 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P97378
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse IL-12 R beta 2 protein Mouse IL-12 R▀2 (Met1-Asn637) Accession # P97378 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
IL-12 receptor beta 2, IL-12 receptor subunit beta-2, IL12R beta 2, IL-12R subunit beta-2, IL12RB2, IL-12RB2, IL-12R-beta-2, interleukin 12 receptor, beta 2, interleukin-12 receptor beta-2 chain, interleukin-12 receptor subunit beta-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.