This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Ephrin-B2 Fc Chimera Protein, CF
catalog :
7397-EB
quantity :
50 ug
price :
339 USD
citations: 11
Reference
Vreeken D, Bruikman C, Cox S, Zhang H, Lalai R, Koudijs A, et al. EPH receptor B2 stimulates human monocyte adhesion and migration independently of its EphrinB ligands. J Leukoc Biol. 2020;: pubmed publisher
Luxan G, Stewen J, Díaz N, Kato K, Maney S, Aravamudhan A, et al. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. elife. 2019;8: pubmed publisher
Hilal R, Poittevin M, Pasteur Rousseau A, Cogo A, Mangin G, Chevauché M, et al. Diabetic Ephrin-B2-Stimulated Peripheral Blood Mononuclear Cells Enhance Poststroke Recovery in Mice. Stem Cells Int. 2018;2018:2431567 pubmed publisher
You C, Zhao K, Dammann P, Keyvani K, Kreitschmann Andermahr I, Sure U, et al. EphB4 forward signalling mediates angiogenesis caused by CCM3/PDCD10-ablation. J Cell Mol Med. 2017;21:1848-1858 pubmed publisher
Fuggetta M, Bordignon V, Cottarelli A, Macchi B, Frezza C, Cordiali Fei P, et al. Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol. J Exp Clin Cancer Res. 2016;35:118 pubmed publisher
Martin Almedina S, Martínez Corral I, Holdhus R, Vicente A, Fotiou E, Lin S, et al. EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. J Clin Invest. 2016;126:3080-8 pubmed publisher
Lisle J, Mertens Walker I, Stephens C, Stansfield S, Clements J, Herington A, et al. Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: implications for xenograft models of human prostate cancer. Exp Cell Res. 2015;333:136-46 pubmed publisher
Kawasaki J, Aegerter S, Fevurly R, Mammoto A, Mammoto T, Sahin M, et al. RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. J Clin Invest. 2014;124:2774-84 pubmed publisher
Grafton K, Moir L, Black J, Hansbro N, Hansbro P, Burgess J, et al. LF-15 & T7, synthetic peptides derived from tumstatin, attenuate aspects of airway remodelling in a murine model of chronic OVA-induced allergic airway disease. PLoS ONE. 2014;9:e85655 pubmed publisher
Liu Q, Stone J, Bradel Tretheway B, Dabundo J, Benavides Montano J, Santos Montanez J, et al. Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry. PLoS Pathog. 2013;9:e1003770 pubmed publisher
Kida Y, Ieronimakis N, Schrimpf C, Reyes M, Duffield J. EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. J Am Soc Nephrol. 2013;24:559-72 pubmed publisher
product information
brand :
R&D Systems
master code :
7397-EB
SKU :
7397-EB-050
product name :
Recombinant Human Ephrin-B2 Fc Chimera Protein, CF
description :
The Recombinant Human Ephrin-B2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Ephrin-B2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Ephrin-B2
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
58-66 kDa, reducing conditions
theoretical molecular weight :
48.8 kDa (monomer)
gene symbol :
EFNB2
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human EphB2 Fc Chimera (Catalog # 5189-B2 ) is coated at 2 µg/mL, Recombinant Human Ephrin-B2 Fc Chimera binds with an apparent Kd 0.1 nM. Also measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neuron.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
7397-EB
accessionNumbers :
P52799
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human Ephrin-B2 protein Human Ephrin-B2 (Met1-Ala229) Accession # P52799 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
2020 USD :
339
2021 USD :
339 USD
alt names :
EFNB2, ELF-2, ephrin B2, EphrinB2, EPLG5, Htk-L, HTKL, LERK5, LERK-5, NLERK-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.