product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse GDF-9 Protein, CF
catalog :
739-G9-010/CF
quantity :
10 ug
price :
453 USD
more info or order :
R&D Systems product webpage
citations: 13
Reference
Ito H, Emori C, Kobayashi M, Maruyama N, Fujii W, Naito K, et al. Cooperative effects of oocytes and estrogen on the forkhead box L2 expression in mural granulosa cells in mice. Sci Rep. 2022;12:20158 pubmed publisher
Luo H, Li X, Tian G, Li D, Hou C, Ding X, et al. Offspring production of ovarian organoids derived from spermatogonial stem cells by defined factors with chromatin reorganization. J Adv Res. 2021;33:81-98 pubmed publisher
Iizuka T, Wakae K, Ono M, Suzuki T, Mizumoto Y, Kitamura K, et al. Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system. Sci Rep. 2021;11:3833 pubmed publisher
Hamazaki N, Kyogoku H, Araki H, Miura F, Horikawa C, Hamada N, et al. Reconstitution of the oocyte transcriptional network with transcription factors. Nature. 2021;589:264-269 pubmed publisher
De los Reyes M, Palomino J, Araujo A, Flores J, Ramirez G, Parraguez V, et al. Cyclooxygenase 2 messenger RNA levels in canine follicular cells: interrelationship with GDF-9, BMP-15, and progesterone. Domest Anim Endocrinol. 2021;74:106529 pubmed publisher
Komatsu K, Masubuchi S. Mouse oocytes connect with granulosa cells by fusing with cell membranes and form a large complex during follicle development. Biol Reprod. 2018;99:527-535 pubmed publisher
El Hayek S, Yang Q, Abbassi L, FitzHarris G, Clarke H. Mammalian Oocytes Locally Remodel Follicular Architecture to Provide the Foundation for Germline-Soma Communication. Curr Biol. 2018;28:1124-1131.e3 pubmed publisher
Kong N, Xu X, Zhang Y, Wang Y, Hao X, Zhao Y, et al. Natriuretic peptide type C induces sperm attraction for fertilization in mouse. Sci Rep. 2017;7:39711 pubmed publisher
Guo J, Shi L, Gong X, Jiang M, Yin Y, Zhang X, et al. Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes. J Cell Sci. 2016;129:3091-103 pubmed publisher
Mottershead D, Sugimura S, Al Musawi S, Li J, Richani D, White M, et al. Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality. J Biol Chem. 2015;290:24007-20 pubmed publisher
Sudiman J, Sutton McDowall M, Ritter L, White M, Mottershead D, Thompson J, et al. Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence. PLoS ONE. 2014;9:e103563 pubmed publisher
Mottershead D, Ritter L, Gilchrist R. Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15. Mol Hum Reprod. 2012;18:121-8 pubmed publisher
Sugiura K, Su Y, Li Q, Wigglesworth K, Matzuk M, Eppig J. Fibroblast growth factors and epidermal growth factor cooperate with oocyte-derived members of the TGFbeta superfamily to regulate Spry2 mRNA levels in mouse cumulus cells. Biol Reprod. 2009;81:833-41 pubmed publisher
image
image 1 :
R&D Systems 739-G9-010/CF image 1
Recombinant Mouse GDF-9 Protein Bioactivity
product information
brand :
R&D Systems
master code :
739-G9/CF
SKU :
739-G9-010/CF
product name :
Recombinant Mouse GDF-9 Protein, CF
description :
The Recombinant Mouse GDF-9 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse GDF-9 Protein, CF has been validated for the following applications: Bioactivity.
target :
GDF-9
category :
Proteins and Enzymes
unit sizes :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in HCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
20 kDa, reducing conditions
theoretical molecular weight :
15.6 kDa
gene symbol :
Gdf9
details of functionality :
Measured by its ability to induce cell death using Mv1Lu mink lung epithelial cells. The ED50 for this effect is 0.1-0.4 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAA53035
applications :
Bioactivity
source :
CHO-derived Recombinant Mouse GDF-9 Protein, CF
USD :
453 USD
alt names :
GDF9, GDF-9, growth differentiation factor 9, growth/differentiation factor 9
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.