Recombinant Mouse LRP-5 Protein | R&D Systems 7344-LR-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse LRP-5 Protein

catalog :

7344-LR-025

quantity :

25 ug

price :

468 USD

citations: 3

Reference
Shay T, Jang S, Brittain T, Chen X, Walker B, Tebbutt C, et al. Human cell surface-AAV interactomes identify LRP6 as blood-brain barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder. Nat Commun. 2024;15:7853 pubmed publisher
Yun J, Hansen S, Morris O, Madden D, Libeu C, Kumar A, et al. Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling. Nat Commun. 2023;14:156 pubmed publisher
Chidiac R, Abedin M, Macleod G, Yang A, Thibeault P, Blazer L, et al. A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy. EMBO Mol Med. 2021;13:e13977 pubmed publisher

product information

master code :

7344-LR

SKU :

7344-LR-025

product name :

Recombinant Mouse LRP-5 Protein

unit size :

25 ug

description :

The Recombinant Mouse LRP-5 Protein from R&D Systems is derived from HEK293. The Recombinant Mouse LRP-5 Protein has been validated for the following applications: Bioactivity.

target :

LRP-5

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

species :

Mouse

observed molecular weight :

160 kDa, reducing conditions

theoretical molecular weight :

152.1 kDa

gene symbol :

Lrp5

details of functionality :

Measured by its binding ability in a functional ELISA. In a Mouse DKK-1 antibody (Catalog # AF1765 ) coated plate, Recombinant Mouse LRP-5 binds Recombinant Mouse DKK-1 (Catalog # 5897-DK ) with an ED50 of 0.150-1.50 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_032539

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived mouse LRP-5 protein Ser31-Ser1383, with a C-terminal 6-His tag

source short :

HEK293

USD :

468 USD

alt names :

BMND1, BMND1OPTA1, EVR1, EVR4, HBM, low density lipoprotein receptor-related protein 5, low density lipoprotein receptor-related protein 7, low-density lipoprotein receptor-related protein 5, LR3VBCH2, LRP5, LRP-5, LRP7, LRP7exudative vitreoretinopathy 1, OPPG, OPS, OPTA1, osteoporosis pseudoglioma syndrome, VBCH2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.