Recombinant Human Laminin alpha 4 Protein, CF | R&D Systems 7340-A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Laminin alpha 4 Protein, CF

catalog :

7340-A4

quantity :

50 ug

price :

389 USD

citations: 3

Reference
Nakamura M, Shiozawa S, Tsuboi D, Amano M, Watanabe H, Maeda S, et al. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. Stem Cell Reports. 2019;13:684-699 pubmed publisher
Burgett M, Lathia J, Roth P, Nowacki A, Galileo D, Pugacheva E, et al. Direct contact with perivascular tumor cells enhances integrin ?v?3 signaling and migration of endothelial cells. Oncotarget. 2016;7:43852-43867 pubmed publisher
Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I, Patarroyo M. Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins. Matrix Biol. 2014;36:5-14 pubmed publisher

product information

brand :

R&D Systems

master code :

7340-A4

SKU :

7340-A4-050

product name :

Recombinant Human Laminin alpha 4 Protein, CF

description :

The Recombinant Human Laminin alpha 4 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Laminin alpha 4 Protein, CF has been validated for the following applications: Bioactivity.

target :

Laminin alpha 4

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

110-120 kDa, reducing conditions

theoretical molecular weight :

111 kDa

gene symbol :

LAMA4

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of HT1080 human fibrosarcoma cells. The ED50 for this effect is 0.7-2.8 µg/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

7340-A4

accessionNumbers :

EAW48267

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human Laminin alpha 4 protein Gln826-Ala1816, with a C-terminal 6-His tag

2020 USD :

369

2021 USD :

389 USD

alt names :

DKFZp686D23145, LAMA3LAMA4*-1, LAMA4, laminin alpha 4 chain, laminin subunit alpha-4, laminin, alpha 4, Laminin-14 subunit alpha, Laminin-8 subunit alpha, Laminin-9 subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.