Recombinant Mouse CD30 Ligand/TNFSF8 Protein | R&D Systems 732-CL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CD30 Ligand/TNFSF8 Protein

catalog :

732-CL-050

quantity :

50 ug

price :

470 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Yoshida S, Nakagami H, Hayashi H, Ikeda Y, Sun J, Tenma A, et al. The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice. Nat Commun. 2020;11:2482 pubmed publisher
Mahmud S, Manlove L, Schmitz H, Xing Y, Wang Y, Owen D, et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat Immunol. 2014;15:473-81 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, et al. TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant. Biochem Biophys Res Commun. 2009;384:296-300 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

732-CL

SKU :

732-CL-050

product name :

Recombinant Mouse CD30 Ligand/TNFSF8 Protein

Description :

The Recombinant Mouse CD30 Ligand/TNFSF8 Protein from R&D Systems is derived from NS0. The Recombinant Mouse CD30 Ligand/TNFSF8 Protein has been validated for the following applications: Bioactivity.

target :

CD30 Ligand/TNFSF8

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

30-45 kDa, reducing conditions

theoretical molecular weight :

22 kDa

gene symbol :

Tnfsf8

details of functionality :

Measured by its ability to stimulate IL-6 secretion by HDLM human Hodgkin’s lymphoma cells. Duckett, C.S. et al . (1997) Mol. Cell. Biol. 17 :1535. The ED50 for this effect is 5-30 ng/mL in the presence of 10 µg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P32972

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse CD30 Ligand/TNFSF8 Protein

USD :

470 USD

alt names :

CD153, CD153 antigen, CD30 antigen ligand, CD30L, CD30-L, CD30LCD30 ligand, CD30LGMGC138144, TNFSF8, tumor necrosis factor (ligand) superfamily, member 8, tumor necrosis factor ligand superfamily member 8

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage