Recombinant Human Pro-Caspase-3 Protein, CF | R&D Systems 731-C3-005 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Pro-Caspase-3 Protein, CF

catalog :

731-C3-005

quantity :

5 ug

price :

480 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Hu L, Huang Z, Ishii H, Wu H, Suzuki S, Inoue A, et al. PLF-1 (Proliferin-1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia. J Am Heart Assoc. 2019;8:e005886 pubmed publisher
Loison F, Zhu H, Karatepe K, Kasorn A, Liu P, Ye K, et al. Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation. J Clin Invest. 2014;124:4445-58 pubmed publisher

product information

master code :

731-C3

SKU :

731-C3-005

product name :

Recombinant Human Pro-Caspase-3 Protein, CF

unit size :

5 ug

description :

The Recombinant Human Pro-Caspase-3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Pro-Caspase-3 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Caspase-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris, NaCl, Sucrose and DTT.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

35 kDa, reducing conditions

theoretical molecular weight :

33 kDa

gene symbol :

CASP3

details of functionality :

The activity of the activated Caspase-3 was measured by its ability to cleave DEVD-AFC. The specific activity is 500 pmol/min/╡g, as measured under the described conditions.

accessionNumbers :

AAA65015

applications :

Enzyme Activity

source long :

E. coli -derived human Caspase-3 protein Met1-His277, with an N-terminal Met and 6-His tag

source short :

E. coli

USD :

480 USD

alt names :

Apopain, apoptosis-related cysteine protease, CASP3, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, Caspase3, CPP32, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, LICE-1, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage