Recombinant Human GCNT1 Protein, CF | R&D Systems 7248-GT-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GCNT1 Protein, CF

catalog :

7248-GT-020

quantity :

20 ug

price :

578 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Wu Z, Ertelt J. Fluorescent glycan fingerprinting of SARS2 spike proteins. Sci Rep. 2021;11:20428 pubmed publisher
Trastoy B, Naegeli A, Anso I, Sjögren J, Guerin M. Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila. Nat Commun. 2020;11:4844 pubmed publisher
Wu Z, Person A, Anderson M, Burroughs B, Tatge T, Khatri K, et al. Imaging specific cellular glycan structures using glycosyltransferases via click chemistry. Glycobiology. 2017;: pubmed publisher
Kojima Y, Yoneyama T, Hatakeyama S, Mikami J, Sato T, Mori K, et al. Detection of Core2 Î²-1,6-N-Acetylglucosaminyltransferase in Post-Digital Rectal Examination Urine Is a Reliable Indicator for Extracapsular Extension of Prostate Cancer. PLoS ONE. 2015;10:e0138520 pubmed publisher

product information

master code :

7248-GT

SKU :

7248-GT-020

product name :

Recombinant Human GCNT1 Protein, CF

unit size :

20 ug

description :

The Recombinant Human GCNT1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human GCNT1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Glucosaminyl (N-acetyl) Transferase 1/GCNT1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and Brij-35.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane.

species :

Human

observed molecular weight :

50-57 kDa, reducing conditions

theoretical molecular weight :

47 kDa

gene symbol :

GCNT1

details of functionality :

Measured by its ability to transfer GlcNAc from UDP-GlcNAc to B1-3 galactosyl-N-acetyl galactosamine. The specific activity is 350 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001481

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human Glucosaminyl (N-acetyl) Transferase 1/GCNT1 protein Arg33-His428, with a C-terminal 6-His tag

source short :

NS0

USD :

578 USD

alt names :

beta-1,3-galactosyl-O-glycosyl-glycoproteinbeta-1,6-N-acetylglucosaminyltransferase, beta-1,6-N-acetylglucosaminyltransferase, C2GNT1, C2GNTbeta-1,3-galactosyl-O-glycosyl-glycoproteinbeta-1,6-N--acetylglucosaminyltransferase, C2GNT-L, core 2 beta1,6 N-acetylglucosaminyltransferase-I, core 2 beta-1,6-N-acetylglucosaminyltransferase I, core 2 branching enzyme, Core 2 GNT, Core 2-branching enzyme, Core2-GlcNAc-transferase, EC 2.4.1.102, G6NT, glucosaminyl (N-acetyl) transferase 1, core 2, glucosaminyl (N-acetyl) transferase 1, core 2(beta-1,6-N-acetylglucosaminyltransferase), MGC126335, MGC126336, NACGT2, NAGCT2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage