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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PKM2 Protein, CF
catalog :
7244-PK-020
quantity :
20 ug
price :
432 USD
more info or order :
citations: 1
Reference
Xu F, Guo M, Huang W, Feng L, Zhu J, Luo K, et al. Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH. Redox Biol. 2020;36:101634 pubmed publisher
product information
master code :
7244-PK
SKU :
7244-PK-020
product name :
Recombinant Human PKM2 Protein, CF
unit size :
20 ug
description :
The Recombinant Human PKM2 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human PKM2 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
PKM2
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris, NaCl, Glycerol, Brij-35 and DTT.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
58-59 kDa, reducing conditions
theoretical molecular weight :
59 kDa
gene symbol :
PKM
details of functionality :
Measured by its ability to transfer phosphate from phospho(enol)pyruvic acid monosodium salt hydrate (PEP) to adenosine 5'-diphosphate sodium salt (ADP). The specific activity is 12,500 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P14618
applications :
Enzyme Activity
source long :
E. coli -derived human PKM2 protein Ser2-Pro531, with N-terminal Met and 6-His tag
source short :
E. coli
extended description :
Pyruvate Kinase, Muscle
USD :
432 USD
product details :
Pyruvate Kinase, Muscle
alt names :
CTHBP, Cytosolic thyroid hormone-binding protein, MGC3932, OIP3, OIP-3, OIP3EC 2.7.1.40, Opa-interacting protein 3, p58, PK, muscle type, PK2, PK3, PK3PKM, Pyruvate kinase 2/3, pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, pyruvate kinase, muscle, TCB, THBP1, THBP1p58, Thyroid hormone-binding protein 1, thyroid hormone-binding protein, cytosolic, Tumor M2-PK
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.