product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse TRAIL R2/TNFRSF10B Fc Chimera Protein, CF
catalog :
721-DR-100
quantity :
100 ug
price :
447 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Luo Y, Hao H, Wang Z, Ong C, Dutcher R, Xu Y, et al. Heparan sulfate promotes TRAIL-induced tumor cell apoptosis. bioRxiv. 2023;: pubmed publisher
Park J, Oh Y, Park Y, Park O, Yang H, Slania S, et al. Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma. Nat Commun. 2019;10:1128 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
721-DR
SKU :
721-DR-100
product name :
Recombinant Mouse TRAIL R2/TNFRSF10B Fc Chimera Protein, CF
Description :
The Recombinant Mouse TRAIL R2/TNFRSF10B Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse TRAIL R2/TNFRSF10B Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TRAIL R2/TNFRSF10B
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
49 kDa, reducing conditions
theoretical molecular weight :
40 kDa (monomer)
gene symbol :
Tnfrsf10b
details of functionality :
Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 3-12 ng/mL in the presence of 20 ng/mL of rhTRAIL or 12 ng/mL cross-linked rhTRAIL (Catalog # 375-TL and MAB050).
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q6GSD9
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Mouse TRAIL R2/TNFRSF10B Fc Chimera Protein
USD :
447 USD
alt names :
CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.