Recombinant Human Wnt-10b Protein | R&D Systems 7196-WN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Wnt-10b Protein

catalog :

7196-WN-010

quantity :

10 ug

price :

662 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Neuhaus J, Weimann A, Berndt Paetz M. Immunocytochemical Analysis of Endogenous Frizzled-(Co-)Receptor Interactions and Rapid Wnt Pathway Activation in Mammalian Cells. Int J Mol Sci. 2021;22: pubmed publisher
Utaijaratrasmi P, Vaeteewoottacharn K, Tsunematsu T, Jamjantra P, Wongkham S, Pairojkul C, et al. The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells. Mol Cancer. 2018;17:10 pubmed publisher
Jang J, Jung Y, Chae S, Chung S, Kim S, Yoon Y. WNT/?-catenin pathway modulates the TNF-?-induced inflammatory response in bronchial epithelial cells. Biochem Biophys Res Commun. 2017;484:442-449 pubmed publisher
Jang J, Jung Y, Kim Y, Jho E, Yoon Y. LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974. Sci Rep. 2017;7:41612 pubmed publisher
Calderon Gierszal E, Prins G. Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure. PLoS ONE. 2015;10:e0133238 pubmed publisher
Kilander M, Dahlström J, Schulte G. Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling and reveals WNT-Frizzled selectivity. Cell Signal. 2014;26:1943-9 pubmed publisher
Thrasivoulou C, Millar M, Ahmed A. Activation of intracellular calcium by multiple Wnt ligands and translocation of ?-catenin into the nucleus: a convergent model of Wnt/Ca2+ and Wnt/?-catenin pathways. J Biol Chem. 2013;288:35651-9 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

7196-WN

SKU :

7196-WN-010

product name :

Recombinant Human Wnt-10b Protein

Description :

The Recombinant Human Wnt-10b Protein from R&D Systems is derived from CHO. The Recombinant Human Wnt-10b Protein has been validated for the following applications: Bioactivity.

target :

Wnt-10b

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS, EDTA and CHAPS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

41 kDa, reducing conditions

theoretical molecular weight :

40 kDa

gene symbol :

WNT10B

details of functionality :

Measured in a cell proliferation/survival assay using IEC-18 rat small intestinal epithelial cells. The ED50 for this effect is 0.3-1.2 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_003385

applications :

Bioactivity

source :

CHO-derived Recombinant Human Wnt-10b Protein

USD :

662 USD

alt names :

protein Wnt-10b, Protein Wnt-12, SHFM6WNT-10B protein, wingless-type MMTV integration site family, member 10B, Wnt10b, Wnt-12, WNT12

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage