product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Wnt-10b Protein, CF
catalog :
7196-WN-010/CF
quantity :
10 ug
price :
662 USD
more info or order :
R&D Systems product webpage
citations: 7
Reference
Neuhaus J, Weimann A, Berndt Paetz M. Immunocytochemical Analysis of Endogenous Frizzled-(Co-)Receptor Interactions and Rapid Wnt Pathway Activation in Mammalian Cells. Int J Mol Sci. 2021;22: pubmed publisher
Utaijaratrasmi P, Vaeteewoottacharn K, Tsunematsu T, Jamjantra P, Wongkham S, Pairojkul C, et al. The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells. Mol Cancer. 2018;17:10 pubmed publisher
Jang J, Jung Y, Chae S, Chung S, Kim S, Yoon Y. WNT/?-catenin pathway modulates the TNF-?-induced inflammatory response in bronchial epithelial cells. Biochem Biophys Res Commun. 2017;484:442-449 pubmed publisher
Jang J, Jung Y, Kim Y, Jho E, Yoon Y. LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974. Sci Rep. 2017;7:41612 pubmed publisher
Calderon Gierszal E, Prins G. Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure. PLoS ONE. 2015;10:e0133238 pubmed publisher
Kilander M, Dahlström J, Schulte G. Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling and reveals WNT-Frizzled selectivity. Cell Signal. 2014;26:1943-9 pubmed publisher
Thrasivoulou C, Millar M, Ahmed A. Activation of intracellular calcium by multiple Wnt ligands and translocation of ?-catenin into the nucleus: a convergent model of Wnt/Ca2+ and Wnt/?-catenin pathways. J Biol Chem. 2013;288:35651-9 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
7196-WN/CF
SKU :
7196-WN-010/CF
product name :
Recombinant Human Wnt-10b Protein, CF
Description :
The Recombinant Human Wnt-10b Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Wnt-10b Protein, CF has been validated for the following applications: Bioactivity.
target :
Wnt-10b
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS, EDTA and CHAPS.
conjugate :
Unconjugated
purity :
>85%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
41 kDa, reducing conditions
theoretical molecular weight :
40 kDa
gene symbol :
WNT10B
details of functionality :
Measured in a cell proliferation/survival assay using IEC-18 rat small intestinal epithelial cells. The ED50 for this effect is 0.3-1.2 µg/mL
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_003385
applications :
Bioactivity
source :
CHO-derived Recombinant Human Wnt-10b Protein
USD :
662 USD
alt names :
protein Wnt-10b, Protein Wnt-12, SHFM6WNT-10B protein, wingless-type MMTV integration site family, member 10B, Wnt10b, Wnt-12, WNT12
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.