Recombinant Human IL-15R alpha Fc Chimera (HEK293), CF | R&D Systems 7194-IR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-15R alpha Fc Chimera (HEK293), CF

catalog :

7194-IR-050

quantity :

50 ug

price :

417 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Schmid A, Neri D. Design and characterisation of a novel interleukin-15 receptor alpha fusion protein and analysis of interleukin-15 complexation. PLoS ONE. 2019;14:e0219313 pubmed publisher
Vicari A, Schoepfer A, Meresse B, Goffin L, Leger O, Josserand S, et al. Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. MAbs. 2017;9:927-944 pubmed publisher

product information

brand :

R&D Systems

master code :

7194-IR

SKU :

7194-IR-050

product name :

Recombinant Human IL-15R alpha Fc Chimera (HEK293), CF

description :

The Recombinant Human IL-15R alpha Fc Chimera (HEK293), CF from R&D Systems is derived from HEK293. The Recombinant Human IL-15R alpha Fc Chimera (HEK293), CF has been validated for the following applications: Bioactivity.

target :

IL-15R alpha

category :

Proteins and Enzymes

unit sizes :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

75-90 kDa, reducing conditions

theoretical molecular weight :

45 kDa (monomer)

gene symbol :

IL15RA

details of functionality :

Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. Ruchatz, H. et al . (1998) J. Immunol. 160 :5654. The ED50 for this effect is 2-10 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q13261

applications :

Bioactivity

source :

HEK293-derived Recombinant Human IL-15R alpha Fc Chimera (HEK293), CF

USD :

417 USD

alt names :

CD215, CD215 antigen, IL15 R alpha, IL-15 R alpha, IL-15 receptor subunit alpha, IL15RA, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage